SCHEMBL7927028

SCHEMBL7927028

[CH]Oc1ccc(CC=NOC)cc1C

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.36
PPARG P37231 1/20 0.36
PPARD Q03181 1/20 0.36
PPARA Q07869 1/20 0.36
CA2 P00918 1/20 0.33
CRHBP P24387 3/20 0.33
CRHR2 Q13324 3/20 0.33
SMN1; SMN2 Q16637 3/20 0.33
MAPT P10636 2/20 0.33
GAA P10253 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
DBH P09172 1/20 0.31
GABRA1 P14867 1/20 0.31
GABRB2 P47870 1/20 0.31
PTGS1 P23219 2/20 0.30
CYP3A4 P08684 1/20 0.30
ALOX5 P09917 1/20 0.30
AR P10275 1/20 0.30
TRPM8 Q7Z2W7 1/20 0.30
ESR1 P03372 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7923048 0.85 ATM (0.33) ALDH1A1CA2CRHBPCRHR2SMN1; SMN2
SCHEMBL7947403 0.70 IDO1 (0.50) ALDH1A1ALOX5
SCHEMBL9264379 0.70 FFAR4 (0.41) PPARGPPARDPPARASMN1; SMN2MAPT
SCHEMBL30536212 0.69 ALDH1A1 (0.50) ALDH1A1PPARGPPARDPPARACA2
SCHEMBL195794 0.69 ALDH1A1 (0.50) ALDH1A1PPARGPPARDPPARACA2
SCHEMBL8059589 0.68
SCHEMBL11741327 0.68 PTGS1 (0.49) ALDH1A1SMN1; SMN2MAPTPTGS1CYP3A4
SCHEMBL5341514 0.67 IDO1 (0.42) ALDH1A1SMN1; SMN2MAPTGAACYP3A4
SCHEMBL6076750 0.67 KDM4E (0.49) ALDH1A1SMN1; SMN2CYP3A4
SCHEMBL1444575 0.67 KDM4E (0.49) ALDH1A1SMN1; SMN2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6221808-B1 Method for controlling parasitic fungi in cultivated plants BASF AKTIENGESELLSCHAFT (DE) 2001-04-24 US claimed