SCHEMBL7927103

SCHEMBL7927103

C=[Ti](OC(C)=O)(OC(C)=O)(C1=CC=CC1)C1c2ccccc2-c2ccccc21

nearest known ligand 0.41

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.41
GAA P10253 1/20 0.32
KMT2A Q03164 2/20 0.31
MEN1 O00255 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7927134 0.89 POLB (0.35) POLB
SCHEMBL7925865 0.87 POLB (0.33) POLBGAA
SCHEMBL7928341 0.86 POLB (0.33) POLBLMNA
SCHEMBL7919133 0.86 POLB (0.33) POLB
SCHEMBL7923901 0.86 KMT2A (0.33) POLBGAAKMT2AMEN1LMNA
SCHEMBL7925529 0.85 POLB (0.32) POLB
SCHEMBL7919194 0.85 LMNA (0.33) POLBKMT2ALMNA
SCHEMBL7919280 0.83 KCNN4 (0.38) POLB
SCHEMBL7930752 0.82 MAPT (0.34) POLBGAAKMT2AMEN1LMNA
SCHEMBL7925779 0.82 POLB (0.39) POLBGAAKMT2AMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0867454-B1 POLYMERIZATION CATALYST AND PROCESS FOR PRODUCING POLYMERS IDEMITSU KOSAN CO (JP) 2001-03-21 EP disclosed
US-6075102-A Polymerization catalyst and process for producing polymers IDEMITSU KOSAN CO., LTD. (JP) 2000-06-13 US disclosed
EP-0867454-A1 POLYMERIZATION CATALYST AND PROCESS FOR PRODUCING POLYMERS IDEMITSU KOSAN COMPANY LIMITED (JP) 1998-09-30 EP disclosed