SCHEMBL7930752

SCHEMBL7930752

C=[Ti](OC(=O)c1ccc(F)cc1)(OC(=O)c1ccc(F)cc1)(C1=CC=CC1)C1c2ccccc2-c2ccccc21

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.34
CASP3 P42574 1/20 0.34
SENP8 Q96LD8 1/20 0.34
SENP7 Q9BQF6 1/20 0.34
SENP6 Q9GZR1 1/20 0.34
HTR2C P28335 2/20 0.32
GAA P10253 3/20 0.32
SLC6A4 P31645 1/20 0.32
SLC6A3 Q01959 1/20 0.32
RAB9A P51151 4/20 0.32
KMT2A Q03164 3/20 0.32
NPC1 O15118 3/20 0.32
MEN1 O00255 2/20 0.32
LMNA P02545 1/20 0.32
PKM P14618 1/20 0.32
POLB P06746 1/20 0.31
PLA2G7 Q13093 1/20 0.31
TERT O14746 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7923901 0.91 KMT2A (0.33) GAAKMT2AMEN1LMNAPOLB
SCHEMBL7930962 0.85 MAPT (0.33) MAPTCASP3SENP8SENP7SENP6
SCHEMBL7927103 0.82 POLB (0.41) GAAKMT2AMEN1LMNAPOLB
SCHEMBL7919299 0.82
SCHEMBL7919200 0.81 RAB9A (0.37) MAPTCASP3SENP8SENP7SENP6
SCHEMBL7925865 0.80 POLB (0.33) MAPTGAAPOLB
SCHEMBL7927134 0.79 POLB (0.35) POLB
SCHEMBL7928341 0.79 POLB (0.33) MAPTLMNAPOLB
SCHEMBL7919133 0.79 POLB (0.33) POLB
SCHEMBL7919260 0.78 KMT2A (0.37) MAPTGAARAB9AKMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0867454-B1 POLYMERIZATION CATALYST AND PROCESS FOR PRODUCING POLYMERS IDEMITSU KOSAN CO (JP) 2001-03-21 EP disclosed
US-6075102-A Polymerization catalyst and process for producing polymers IDEMITSU KOSAN CO., LTD. (JP) 2000-06-13 US disclosed
EP-0867454-A1 POLYMERIZATION CATALYST AND PROCESS FOR PRODUCING POLYMERS IDEMITSU KOSAN COMPANY LIMITED (JP) 1998-09-30 EP disclosed