Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | PNMT | P11086 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7927106 | 0.90 | NPC1 (0.41) | NPC1RAB9AHTR2BHTR7PNMT | |
| SCHEMBL7919474 | 0.89 | RAB9A (0.46) | NPC1RAB9AHTR2BHTR7PNMT | |
| SCHEMBL7928345 | 0.86 | NPC1 (0.38) | NPC1RAB9AHTR2BHTR7PNMT | |
| SCHEMBL7925868 | 0.85 | NPC1 (0.37) | NPC1RAB9AHTR2BHTR7PNMT | |
| SCHEMBL7919135 | 0.85 | NPC1 (0.39) | NPC1RAB9AHTR2BHTR7PNMT | |
| SCHEMBL7923902 | 0.85 | NPC1 (0.37) | NPC1RAB9AHTR2BHTR7PNMT | |
| SCHEMBL7925530 | 0.84 | NPC1 (0.36) | NPC1RAB9AHTR2BHTR7 | |
| SCHEMBL7919196 | 0.84 | NPC1 (0.36) | NPC1RAB9AHTR2BHTR7PNMT | |
| SCHEMBL7919285 | 0.82 | NPC1 (0.35) | NPC1RAB9AHTR2BHTR7 | |
| SCHEMBL7930755 | 0.82 | MAPT (0.35) | NPC1RAB9AHTR2BHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0867454-B1 | POLYMERIZATION CATALYST AND PROCESS FOR PRODUCING POLYMERS | IDEMITSU KOSAN CO (JP) | 2001-03-21 | — | — | EP | disclosed |
| US-6075102-A | Polymerization catalyst and process for producing polymers | IDEMITSU KOSAN CO., LTD. (JP) | 2000-06-13 | — | — | US | disclosed |
| EP-0867454-A1 | POLYMERIZATION CATALYST AND PROCESS FOR PRODUCING POLYMERS | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1998-09-30 | — | — | EP | disclosed |