SCHEMBL7930755

SCHEMBL7930755

C=[Ti](OC(=O)c1ccc(F)cc1)(OC(=O)c1ccc(F)cc1)(C1=CC=CC1)c1cccc2c1Cc1ccccc1-2

nearest known ligand 0.36

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.35
CASP3 P42574 1/20 0.35
SENP8 Q96LD8 1/20 0.35
SENP7 Q9BQF6 1/20 0.35
SENP6 Q9GZR1 1/20 0.35
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
GAA P10253 1/20 0.32
SRD5A2 P31213 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
HTR7 P34969 1/20 0.31
HTR2B P41595 1/20 0.31
SQOR Q9Y6N5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7923902 0.92 NPC1 (0.37) NPC1RAB9ASRD5A2MEN1KMT2A
SCHEMBL7927572 0.89 MAPT (0.40) MAPTCASP3SENP8SENP7SENP6
SCHEMBL7927106 0.84 NPC1 (0.41) MAPTNPC1RAB9ASRD5A2MEN1
SCHEMBL7928345 0.83 NPC1 (0.38) NPC1RAB9ASRD5A2HTR7HTR2B
SCHEMBL7927137 0.82 NPC1 (0.39) NPC1RAB9AHTR7HTR2B
SCHEMBL7925868 0.82 NPC1 (0.37) MAPTNPC1RAB9AGAAMEN1
SCHEMBL7919135 0.82 NPC1 (0.39) MAPTNPC1RAB9AHTR7HTR2B
SCHEMBL7919262 0.82 HTR7 (0.34) MAPTNPC1RAB9AGAAMEN1
SCHEMBL7919196 0.81 NPC1 (0.36) MAPTNPC1RAB9AGAAMEN1
SCHEMBL7925530 0.81 NPC1 (0.36) NPC1RAB9AHTR7HTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0867454-B1 POLYMERIZATION CATALYST AND PROCESS FOR PRODUCING POLYMERS IDEMITSU KOSAN CO (JP) 2001-03-21 EP disclosed
US-6075102-A Polymerization catalyst and process for producing polymers IDEMITSU KOSAN CO., LTD. (JP) 2000-06-13 US disclosed
EP-0867454-A1 POLYMERIZATION CATALYST AND PROCESS FOR PRODUCING POLYMERS IDEMITSU KOSAN COMPANY LIMITED (JP) 1998-09-30 EP disclosed