SCHEMBL7927320

SCHEMBL7927320

CCC(Cl)CCC(Cl)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.43
TSHR P16473 1/20 0.41
HRH1 P35367 4/20 0.36
HTR2A P28223 3/20 0.36
SIGMAR1 Q99720 1/20 0.36
MIF P14174 1/20 0.36
HSD17B10 Q99714 1/20 0.36
DPP4 P27487 2/20 0.36
F2 P00734 1/20 0.36
HKDC1 Q2TB90 1/20 0.35
TRPA1 O75762 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22042229 0.84 TSHR (0.55) TSHRHRH1HTR2ADPP4F2
SCHEMBL2239367 0.80 TSHR (0.46) LMNATSHRHRH1HTR2ASIGMAR1
SCHEMBL9441134 0.80 TSHR (0.46) LMNATSHRHRH1HTR2ASIGMAR1
SCHEMBL212179 0.80 LMNA (0.52) LMNATSHRHRH1HTR2AMIF
SCHEMBL13594208 0.80 LMNA (0.52) LMNATSHRHRH1HTR2AMIF
SCHEMBL18585352 0.78 LMNA (0.50) LMNATSHRHRH1HTR2AMIF
SCHEMBL1374200 0.77 POLB (0.45) LMNATSHRHRH1HTR2ASIGMAR1
SCHEMBL4306863 0.75 SIGMAR1 (0.44) LMNATSHRHRH1HTR2ASIGMAR1
SCHEMBL22042223 0.75 TSHR (0.50) TSHRHRH1HTR2ASIGMAR1DPP4
Dimethylamine SCHEMBL28043822 0.74 LMNA (0.46) LMNATSHRHRH1HTR2AMIF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6235679-B1 HEATING INK SHEETS; CONTROLLING OPTICAL DENSITY KONICA CORPORATION (JP) 2001-05-22 US disclosed