SCHEMBL7927901

SCHEMBL7927901

CCCCCCCC(C(=O)Cl)C(=O)Cl

nearest known ligand 0.53

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 7/20 0.50
FFAR1 O14842 2/20 0.50
ALDH1A1 P00352 1/20 0.50
TSHR P16473 1/20 0.50
MAPT P10636 1/20 0.48
LCK P06239 1/20 0.48
PPARD Q03181 1/20 0.48
ZDHHC20 Q5W0Z9 1/20 0.48
ZDHHC2 Q9UIJ5 1/20 0.48
CA2 P00918 1/20 0.47
FFAR4 Q5NUL3 1/20 0.45
ACE2 Q9BYF1 1/20 0.45
FDPS P14324 3/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9195568 1.00 GPR84 (0.50) GPR84FFAR1ALDH1A1TSHRMAPT
SCHEMBL11158524 1.00 GPR84 (0.50) GPR84FFAR1ALDH1A1TSHRMAPT
SCHEMBL11151125 1.00 GPR84 (0.50) GPR84FFAR1ALDH1A1TSHRMAPT
SCHEMBL9622165 1.00 GPR84 (0.50) GPR84FFAR1ALDH1A1TSHRMAPT
SCHEMBL9778087 1.00 GPR84 (0.50) GPR84FFAR1ALDH1A1TSHRMAPT
SCHEMBL9462908 1.00 GPR84 (0.50) GPR84FFAR1ALDH1A1TSHRMAPT
SCHEMBL12961264 0.98 GPR84 (0.46) GPR84FFAR1ALDH1A1TSHRMAPT
SCHEMBL28104759 0.91 GPR84 (0.57) GPR84FFAR1ALDH1A1TSHRMAPT
SCHEMBL39527 0.90 ALDH1A1 (0.46) GPR84FFAR1ALDH1A1TSHRCA2
SCHEMBL27438256 0.86 ALDH1A1 (0.52) FFAR1ALDH1A1TSHRFFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103889563-A Composite polyamide membranes derived from carboxylic acid-containing acyl halide monomers DOW GLOBAL TECHNOLOGIES INC 2014-06-25 CN disclosed
US-20120271003-A1 Block Copolymers As Thermoplastic Elastomers Made Of Polyisobutene Blocks And Oligoamide Blocks BASF SE (DE) 2012-10-25 US disclosed
EP-1085893-A1 PHOSPHODIESTERASE-V MODULATOR DRUGS AND THEIR USES Advanced Medicine, Inc. (US) 2001-03-28 EP disclosed
WO-1999064033-A1 PHOSPHODIESTERASE-V MODULATOR DRUGS AND THEIR USES ADVANCED MEDICINE, INC. (US) 1999-12-16 WO disclosed
US-4388246-A THERMAL SPLITTING OF CARBAMATES BAYER AKTIENGESELLSCHAFT (DE) 1983-06-14 US disclosed