Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MT-CO2 | P00403 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13148722 | 1.00 | MT-CO2 (0.46) | MT-CO2RAB9ANPC1SMN1; SMN2RECQL | |
| SCHEMBL922803 | 1.00 | MT-CO2 (0.46) | MT-CO2RAB9ANPC1SMN1; SMN2RECQL | |
| SCHEMBL28440815 | 0.93 | ATM (0.46) | MT-CO2RAB9ANPC1SMN1; SMN2RECQL | |
| SCHEMBL517256 | 0.93 | MT-CO2 (0.42) | MT-CO2RAB9ANPC1SMN1; SMN2RECQL | |
| SCHEMBL7930497 | 0.92 | MT-CO2 (0.41) | MT-CO2RAB9ANPC1SMN1; SMN2RECQL | |
| SCHEMBL16523071 | 0.91 | KDM4E (0.40) | MT-CO2RAB9ANPC1SMN1; SMN2RECQL | |
| SCHEMBL7929176 | 0.91 | RAB9A (0.50) | MT-CO2RAB9ANPC1SMN1; SMN2RECQL | |
| SCHEMBL16627083 | 0.89 | ATM (0.42) | MT-CO2RAB9ANPC1SMN1; SMN2RECQL | |
| SCHEMBL516526 | 0.89 | MT-CO2 (0.40) | MT-CO2RAB9ANPC1SMN1; SMN2RECQL | |
| SCHEMBL14740797 | 0.86 | RAB9A (0.41) | MT-CO2RAB9ANPC1SMN1; SMN2RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235871-B1 | Synthesis of oligoarylamines, and uses and reagents related thereto | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2001-05-22 | — | — | US | disclosed |