Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 7/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3206099 | 0.92 | EPHX2 (0.52) | LTB4REPHX2FABP5KMT2ALMNA | |
| SCHEMBL18103625 | 0.90 | EPHX2 (0.50) | LTB4REPHX2FABP5KMT2AHDAC1 | |
| SCHEMBL30522780 | 0.87 | EPHX2 (0.56) | EPHX2FABP5KMT2AMEN1POLB | |
| SCHEMBL25397265 | 0.87 | EPHX2 (0.56) | EPHX2FABP5KMT2AMEN1POLB | |
| SCHEMBL570236 | 0.86 | EPHX2 (0.53) | EPHX2KMT2AMEN1PPARGGAA | |
| SCHEMBL31173117 | 0.85 | EPHX2 (0.52) | EPHX2FABP5KMT2AMEN1LMNA | |
| SCHEMBL29547060 | 0.85 | EPHX2 (0.52) | EPHX2FABP5KMT2AMEN1POLB | |
| SCHEMBL29546978 | 0.85 | EPHX2 (0.52) | EPHX2FABP5KMT2AMEN1POLB | |
| SCHEMBL26628373 | 0.85 | EPHX2 (0.52) | EPHX2FABP5KMT2AMEN1POLB | |
| SCHEMBL3209502 | 0.85 | EPHX2 (0.57) | EPHX2FABP5KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160279108-A1 | TARGETED MTOR INHIBITORS | UNIVERSITY OF KANSAS (US) | 2016-09-29 | — | — | US | disclosed |
| US-20160279108-A1 | TARGETED MTOR INHIBITORS | UNIVERSITY OF KANSAS (US) | 2016-09-29 | — | — | US | disclosed |
| US-8802235-B2 | Drug and imaging agent delivery compositions and methods | UNIVERSITY OF KANSAS (US) | 2014-08-12 | — | — | US | disclosed |
| US-20130189519-A1 | Drug and Imaging Agent Delivery Compositions and Methods | UNIVERSITY OF KANSAS (US) | 2013-07-25 | — | — | US | disclosed |
| WO-2013109907-A1 | DRUG AND IMAGING AGENT DELIVERY COMPOSITIONS AND METHODS | UNIVERSITY OF KANSAS (US) | 2013-07-25 | — | — | WO | disclosed |
| US-6228868-B1 | ANTICARCINOGENIC AND ANTITUMOR AGENTS | ABBOTT LABORATORIES | 2001-05-08 | — | — | US | disclosed |
| WO-2000006556-A1 | SUBSTITUTED OXAZOLINES AS ANTIPROLIFERATIVE AGENTS | ABBOTT LABORATORIES (US) | 2000-02-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130189519-A1 | Drug and Imaging Agent Delivery Compositions and Methods | STARD10, STARD7, CASP10 | LTB4R 1924/4885EPHX2 3282/4885FABP5 4631/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.