Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.57 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.55 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.55 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.55 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CETP | P11597 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1030263 | 0.85 | LMNA (0.74) | LMNAKDM4EALOX12PDK1PDK2 | |
| SCHEMBL18021884 | 0.83 | LMNA (0.58) | LMNAKDM4EALOX12PDK1PDK2 | |
| SCHEMBL8140708 | 0.81 | KDM4E (0.57) | LMNAKDM4EALOX12PDK1PDK2 | |
| SCHEMBL10046356 | 0.81 | KDM4E (0.57) | LMNAKDM4EALOX12PDK1PDK2 | |
| SCHEMBL1983314 | 0.81 | KDM4E (0.57) | LMNAKDM4EALOX12PDK1PDK2 | |
| SCHEMBL8806924 | 0.80 | CA12 (0.59) | LMNAKDM4EALOX12PDK1PDK2 | |
| SCHEMBL9872617 | 0.80 | KDM4E (0.56) | LMNAKDM4EALOX12PDK1PDK2 | |
| SCHEMBL23888203 | 0.79 | LMNA (0.55) | LMNAKDM4EALOX12PDK1PDK2 | |
| SCHEMBL4171512 | 0.79 | LMNA (0.55) | LMNAKDM4EALOX12PDK1PDK2 | |
| SCHEMBL4722310 | 0.79 | LMNA (0.55) | LMNAKDM4EALOX12PDK1PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010033444-A1 | CRYSTALLINE FORMS OF A 2-THIAZOLYL- 4-QUINOLINYL-OXY DERIVATIVE, A POTENT HCV INHIBITOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-03-25 | — | — | WO | disclosed |