SCHEMBL7928041

SCHEMBL7928041

CCOC(=O)C(F)(CCC(F)(F)C(F)(F)C(F)(F)C(F)(F)F)C(F)(F)F

nearest known ligand 0.36

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.36
KMT2A Q03164 2/20 0.36
POLB P06746 2/20 0.36
KDM4E B2RXH2 2/20 0.36
MEN1 O00255 1/20 0.35
TSHR P16473 2/20 0.35
CYP4F2 P78329 2/20 0.34
CYP4A11 Q02928 2/20 0.34
PKM P14618 2/20 0.34
THRB P10828 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
HTT P42858 2/20 0.33
HIF1A Q16665 1/20 0.33
ALDH1A1 P00352 2/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
TRPA1 O75762 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1235041 0.84 TSHR (0.38) MAPTKMT2APOLBKDM4EMEN1
SCHEMBL1233377 0.83 TSHR (0.38) MAPTKMT2APOLBKDM4EMEN1
SCHEMBL7931466 0.78 CYP4F2 (0.37) MAPTKMT2APOLBKDM4EMEN1
SCHEMBL7254521 0.78 CYP4F2 (0.37) MAPTKMT2APOLBKDM4EMEN1
SCHEMBL9509807 0.77 MEN1 (0.44) MAPTKMT2APOLBMEN1CYP4F2
SCHEMBL7255413 0.76 KMT2A (0.41) MAPTKMT2APOLBKDM4EMEN1
SCHEMBL12555642 0.75 POLB (0.44) MAPTKMT2APOLBKDM4EMEN1
SCHEMBL17626380 0.75 TRPA1 (0.42) MAPTKMT2APOLBKDM4ETSHR
SCHEMBL9510951 0.75 MEN1 (0.50) MAPTKMT2AMEN1CYP4F2CYP4A11
SCHEMBL9508242 0.74 MEN1 (0.53) MAPTKMT2AMEN1CYP4F2CYP4A11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0822175-B1 Hydrogen-containing fluorosurfactant and its use in polymerisation DU PONT (US) 2001-05-16 EP disclosed
US-5763552-A Hydrogen-containing flourosurfacant and its use in polymerization E. I. DU PONT DE NEMOURS AND COMPANY (US) 1998-06-09 US disclosed
EP-0822175-A2 Hydrogen-containing fluorosurfactant and its use in polymerisation E.I. DU PONT DE NEMOURS AND COMPANY (US) 1998-02-04 EP disclosed