Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.32 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.32 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1130 | 1.00 | TSHR (0.43) | TSHRLMNATHRBALDH1A1TDP1 | |
| SCHEMBL30633598 | 0.96 | TSHR (0.46) | TSHRLMNATHRBALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL8555733 | 0.93 | TSHR (0.38) | TSHRLMNATHRBALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL9716516 | 0.93 | TSHR (0.38) | TSHRLMNATHRBALDH1A1TDP1 | |
| SCHEMBL6750642 | 0.92 | TSHR (0.43) | TSHRLMNATHRBALDH1A1TDP1 | |
| SCHEMBL910536 | 0.92 | TSHR (0.43) | TSHRLMNATHRBALDH1A1TDP1 | |
| Fluoride Ion SCHEMBL394141 | 0.92 | TSHR (0.43) | TSHRLMNATHRBALDH1A1TDP1 | |
| Bromide SCHEMBL2345 | 0.92 | TSHR (0.43) | TSHRLMNATHRBALDH1A1TDP1 | |
| Hydrogen Sulfide SCHEMBL10730186 | 0.92 | TSHR (0.43) | TSHRLMNATHRBALDH1A1TDP1 | |
| Iodide SCHEMBL578857 | 0.92 | TSHR (0.43) | TSHRLMNATHRBALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114772945-B | Coated fireproof glass with sunlight control and low radiation functions and preparation method thereof | 中国耀华玻璃集团有限公司 | 2024-04-16 | — | — | CN | claimed |
| CN-111732805-A | Chitosan-doped polyester material and preparation method thereof | 宣城市创道智能技术开发有限责任公司 | 2020-10-02 | — | — | CN | claimed |
| CN-114772945-B | Coated fireproof glass with sunlight control and low radiation functions and preparation method thereof | 中国耀华玻璃集团有限公司 | 2024-04-16 | — | — | CN | disclosed |
| CN-117756415-A | Preparation method of composite coated glass and solar cell | 漳州旗滨玻璃有限公司 | 2024-03-26 | — | — | CN | disclosed |
| CN-116848674-A | Binder for all-solid secondary battery, binder composition for all-solid secondary battery, slurry for all-solid secondary battery, solid electrolyte sheet for all-solid secondary battery, method for producing same, and all-solid secondary battery | 株式会社引能仕材料 | 2023-10-03 | — | — | CN | disclosed |
| CN-116783735-A | Binder for all-solid secondary battery, binder composition for all-solid secondary battery, slurry for all-solid secondary battery, solid electrolyte sheet for all-solid secondary battery, method for producing same, and all-solid secondary battery | 株式会社引能仕材料 | 2023-09-19 | — | — | CN | disclosed |
| CN-110818975-B | Modified conjugated diene polymer composition, method for producing modified conjugated diene polymer composition, and tire | 旭化成株式会社 | 2022-04-01 | — | — | CN | disclosed |
| CN-111732805-A | Chitosan-doped polyester material and preparation method thereof | 宣城市创道智能技术开发有限责任公司 | 2020-10-02 | — | — | CN | disclosed |
| CN-111527167-A | Surface protection sheet for optical member | 日东电工株式会社 | 2020-08-11 | — | — | CN | disclosed |
| CN-110818975-A | Modified conjugated diene polymer composition, method for producing modified conjugated diene polymer composition, and tire | 旭化成株式会社 | 2020-02-21 | — | — | CN | disclosed |
| CN-110551475-A | Adhesive composition, adhesive layer, and protective film | NITTO DENKO CORP | 2019-12-10 | — | — | CN | disclosed |
| CN-104845293-A | High-hardness plastic container | ANHUI JIAYI LEISURE GOODS CO LTD | 2015-08-19 | — | — | CN | disclosed |
| CN-104403321-A | Silicone rubber die material for alloy production | CHUZHOU JUNYUE HIGH POLMER NEW MATERIAL INDUSTRY CO LTD | 2015-03-11 | — | — | CN | disclosed |
| CN-104250501-A | Environment-friendly anti-radiation waterproof paint for exterior walls | ANHUI SANGRUISI ENVIRONMENTAL PROT NEW MATERIAL CO LTD | 2014-12-31 | — | — | CN | disclosed |
| CN-104140646-A | Halogen-free antioxidant pbt material | CHUZHOU YOUSHENG HIGH POLYMER MATERIAL CO LTD | 2014-11-12 | — | — | CN | disclosed |
| CN-104109434-A | Inorganic anti-stripping paint | WUHU LANGRUN NEW MATERIAL CO LTD | 2014-10-22 | — | — | CN | disclosed |
| US-8859690-B2 | Biodegradable composite, the preparation process thereof, and a disposable article made therefrom | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2014-10-14 | — | — | US | disclosed |
| CN-103773091-A | High-hardness polypropylene powder coating | WUHU BAOYI AMUSEMENT EQUIPMENT CO LTD | 2014-05-07 | — | — | CN | disclosed |
| US-20120329924-A1 | Biodegradable Composite, The Preparation Process Thereof, And A Disposable Article Made Therefrom | BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2012-12-27 | — | — | US | disclosed |
| US-6248899-B1 | Transesterification catalysts fixed to solid support materials | CIBA SPECIALTY CHEMICALS CORPORATION | 2001-06-19 | — | — | US | disclosed |