Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1130 | 0.93 | TSHR (0.43) | TSHRLMNATHRBALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL7928153 | 0.93 | TSHR (0.43) | TSHRLMNATHRBALDH1A1TDP1 | |
| SCHEMBL30633598 | 0.89 | TSHR (0.46) | TSHRLMNATHRBALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL8555733 | 0.87 | TSHR (0.38) | TSHRLMNATHRBALDH1A1TDP1 | |
| Hydrogen Sulfide SCHEMBL10730186 | 0.86 | TSHR (0.43) | TSHRLMNATHRBALDH1A1TDP1 | |
| SCHEMBL910536 | 0.86 | TSHR (0.43) | TSHRLMNATHRBALDH1A1TDP1 | |
| Bromide SCHEMBL2345 | 0.86 | TSHR (0.43) | TSHRLMNATHRBALDH1A1TDP1 | |
| Fluoride Ion SCHEMBL394141 | 0.86 | TSHR (0.43) | TSHRLMNATHRBALDH1A1TDP1 | |
| SCHEMBL6750642 | 0.86 | TSHR (0.43) | TSHRLMNATHRBALDH1A1TDP1 | |
| SCHEMBL411338 | 0.86 | TSHR (0.43) | TSHRLMNATHRBALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0247019-B1 | ANTIFOULING AND ANTICORROSIVE COATING FOR UNDERWATER STRUCTURES | FINA RESEARCH S.A. (BE) | 1992-04-15 | — | — | EP | disclosed |
| EP-0247019-A2 | Antifouling and anticorrosive coating for underwater structures | FINA RESEARCH S.A. (BE) | 1987-11-25 | — | — | EP | disclosed |