SCHEMBL7928206

SCHEMBL7928206

Oc1cccc(Br)c1.Oc1ccccc1Br

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.46
ALDH1A1 P00352 3/20 0.44
CYP3A4 P08684 3/20 0.44
CA12 O43570 2/20 0.44
CA2 P00918 2/20 0.44
CA9 Q16790 2/20 0.44
CA14 Q9ULX7 2/20 0.44
LMNA P02545 1/20 0.44
CA5A P35218 1/20 0.44
HSD17B10 Q99714 1/20 0.44
CA5B Q9Y2D0 1/20 0.44
NPC1 O15118 1/20 0.44
P2RX1 P51575 1/20 0.41
GSTA1 P08263 1/20 0.39
CXCR1 P25024 1/20 0.38
CTSL P07711 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP2C19 P33261 1/20 0.37
CXCR2 P25025 1/20 0.37
TSHR P16473 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL49927 0.84
SCHEMBL29505543 0.84
Phenol SCHEMBL6638822 0.82 CA12 (0.55) ALOX15ALDH1A1CYP3A4CA12CA2
Resorcinol SCHEMBL29270362 0.82 ALDH1A1 (0.67) ALOX15ALDH1A1CYP3A4CA12CA2
Phosphine SCHEMBL4337915 0.82
SCHEMBL28644412 0.82
Phenol SCHEMBL5316209 0.80 CA2 (0.58) ALOX15ALDH1A1CYP3A4CA12CA2
SCHEMBL3440828 0.79 ALDH1A1 (0.56) ALOX15ALDH1A1CYP3A4CA12CA2
SCHEMBL49313 0.79
SCHEMBL15059320 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1153938-A1 CATALYST FOR STEREOREGULAR POLYMERIZATION OF ALPHA-OLEFIN AND PROCESS FOR PRODUCING STEREOREGULAR ALPHA-OLEFIN POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-11-14 EP disclosed