Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.76 |
| ▸ | GAA | P10253 | 1/20 | 0.73 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | HRH2 | P25021 | 1/20 | 0.51 |
| ▸ | HRH1 | P35367 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20148862 | 0.87 | L3MBTL1 (0.79) | L3MBTL1GAAMAPTALDH1A1LMNA | |
| SCHEMBL18868405 | 0.87 | L3MBTL1 (1.00) | L3MBTL1GAAMAPTALDH1A1LMNA | |
| SCHEMBL445511 | 0.86 | L3MBTL1 (0.76) | L3MBTL1GAAMAPTALDH1A1LMNA | |
| SCHEMBL834525 | 0.85 | L3MBTL1 (0.88) | L3MBTL1GAAMAPTALDH1A1LMNA | |
| SCHEMBL26241763 | 0.84 | L3MBTL1 (0.79) | L3MBTL1GAAMAPTALDH1A1LMNA | |
| SCHEMBL31270955 | 0.83 | L3MBTL1 (0.67) | L3MBTL1GAAMAPTALDH1A1LMNA | |
| SCHEMBL1092185 | 0.83 | L3MBTL1 (0.85) | L3MBTL1GAAMAPTALDH1A1LMNA | |
| SCHEMBL21541008 | 0.83 | L3MBTL1 (0.57) | L3MBTL1GAAMAPTALDH1A1LMNA | |
| SCHEMBL11456703 | 0.83 | L3MBTL1 (0.71) | L3MBTL1GAAMAPTALDH1A1LMNA | |
| SCHEMBL8488482 | 0.82 | L3MBTL1 (0.82) | L3MBTL1GAAMAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010039256-A1 | 2-ACYLAMINOPROPOANOL-TYPE GLUCOSYLCERAMIDE SYNTHASE INHIBITORS | GENZYME CORPORATION (US) | 2010-04-08 | — | — | WO | disclosed |