SCHEMBL7928243

SCHEMBL7928243

CCCC(=O)O[Ti](OC(=O)CCC)(C1C=Cc2ccccc21)(C1C=Cc2ccccc21)=[Si](C)C

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
RET P07949 1/20 0.36
LMNA P02545 2/20 0.32
ALDH1A1 P00352 1/20 0.32
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
RECQL P46063 1/20 0.32
KMT2A Q03164 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7925599 0.90 RET (0.37) RETLMNASMN1; SMN2
SCHEMBL7930984 0.83 POLB (0.34) RETALDH1A1KDM4EMEN1KMT2A
SCHEMBL7930981 0.82 RET (0.34) RETLMNAALDH1A1SMN1; SMN2
SCHEMBL7924668 0.80 RET (0.33) RETLMNAALDH1A1SMN1; SMN2
SCHEMBL7925640 0.80 TSHR (0.36) RETLMNAALDH1A1MEN1KMT2A
SCHEMBL7925499 0.79 RET (0.33) RETLMNA
SCHEMBL7928111 0.79
SCHEMBL7930275 0.78 KCNN4 (0.41)
SCHEMBL7925441 0.76 KMT2A (0.37) LMNAALDH1A1KDM4EMEN1KMT2A
SCHEMBL7925895 0.76 NPC1 (0.35) MEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0867454-B1 POLYMERIZATION CATALYST AND PROCESS FOR PRODUCING POLYMERS IDEMITSU KOSAN CO (JP) 2001-03-21 EP disclosed
US-6075102-A Polymerization catalyst and process for producing polymers IDEMITSU KOSAN CO., LTD. (JP) 2000-06-13 US disclosed
EP-0867454-A1 POLYMERIZATION CATALYST AND PROCESS FOR PRODUCING POLYMERS IDEMITSU KOSAN COMPANY LIMITED (JP) 1998-09-30 EP disclosed