SCHEMBL7925640

SCHEMBL7925640

C[Si](C)=[Ti](OC(=O)c1ccccc1)(OC(=O)c1ccccc1)(C1C=Cc2ccccc21)C1C=Cc2ccccc21

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.36
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
LMNA P02545 2/20 0.34
F2 P00734 1/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
ATM Q13315 1/20 0.33
TDP1 Q9NUW8 2/20 0.32
ALDH1A1 P00352 1/20 0.32
HSD17B10 Q99714 1/20 0.32
TP53 P04637 1/20 0.30
GAA P10253 1/20 0.30
RET P07949 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7925895 0.90 NPC1 (0.35) TSHRMEN1KMT2ANPC1RAB9A
SCHEMBL7930984 0.85 POLB (0.34) MEN1KMT2AATMALDH1A1HSD17B10
SCHEMBL7930275 0.82 KCNN4 (0.41)
SCHEMBL7925599 0.82 RET (0.37) LMNARET
SCHEMBL7925441 0.81 KMT2A (0.37) MEN1KMT2ALMNANPC1RAB9A
SCHEMBL7928111 0.81
SCHEMBL7927202 0.80 LMNA (0.37) TSHRMEN1KMT2ALMNAF2
SCHEMBL7928243 0.80 RET (0.36) MEN1KMT2ALMNAALDH1A1RET
SCHEMBL7924743 0.79 TSHR (0.36) TSHRMEN1KMT2ALMNAF2
SCHEMBL7930341 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0867454-B1 POLYMERIZATION CATALYST AND PROCESS FOR PRODUCING POLYMERS IDEMITSU KOSAN CO (JP) 2001-03-21 EP disclosed
US-6075102-A Polymerization catalyst and process for producing polymers IDEMITSU KOSAN CO., LTD. (JP) 2000-06-13 US disclosed
EP-0867454-A1 POLYMERIZATION CATALYST AND PROCESS FOR PRODUCING POLYMERS IDEMITSU KOSAN COMPANY LIMITED (JP) 1998-09-30 EP disclosed