SCHEMBL7930984

SCHEMBL7930984

CC(=O)O[Ti](OC(C)=O)(C1C=Cc2ccccc21)(C1C=Cc2ccccc21)=[Si](C)C

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.34
BRD4 O60885 1/20 0.34
CCL2 P13500 1/20 0.34
MEN1 O00255 3/20 0.32
ALDH1A1 P00352 3/20 0.32
MAPT P10636 3/20 0.32
HPGD P15428 3/20 0.32
KMT2A Q03164 3/20 0.32
KDM4E B2RXH2 2/20 0.32
RET P07949 1/20 0.32
CYP2C9 P11712 2/20 0.31
CYP2C19 P33261 2/20 0.31
HSD17B10 Q99714 1/20 0.31
USP2 O75604 1/20 0.31
ALOX15 P16050 1/20 0.31
CASP1 P29466 1/20 0.31
CASP7 P55210 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
HTR2A P28223 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7925599 0.85 RET (0.37) RETCYP1A2HTR2A
SCHEMBL7925640 0.85 TSHR (0.36) MEN1ALDH1A1KMT2ARETHSD17B10
SCHEMBL7928111 0.84
SCHEMBL7928243 0.83 RET (0.36) MEN1ALDH1A1KMT2AKDM4ERET
SCHEMBL7930275 0.83 KCNN4 (0.41)
SCHEMBL7925895 0.81 NPC1 (0.35) POLBMEN1MAPTKMT2ACYP2C19
SCHEMBL7927560 0.79 POLB (0.36) POLBBRD4CCL2MEN1ALDH1A1
SCHEMBL7925441 0.79 KMT2A (0.37) POLBMEN1ALDH1A1MAPTHPGD
SCHEMBL7927213 0.78 BRD4 (0.32) BRD4CCL2HTR2A
SCHEMBL7927789 0.77 POLB (0.34) POLBBRD4CCL2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0867454-B1 POLYMERIZATION CATALYST AND PROCESS FOR PRODUCING POLYMERS IDEMITSU KOSAN CO (JP) 2001-03-21 EP disclosed
US-6075102-A Polymerization catalyst and process for producing polymers IDEMITSU KOSAN CO., LTD. (JP) 2000-06-13 US disclosed
EP-0867454-A1 POLYMERIZATION CATALYST AND PROCESS FOR PRODUCING POLYMERS IDEMITSU KOSAN COMPANY LIMITED (JP) 1998-09-30 EP disclosed