SCHEMBL7928274

SCHEMBL7928274

CCCOc1cccc(OCCC)c1[NH]

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCHR1 Q99705 2/20 0.47
CYP2A6 P11509 1/20 0.46
CYP1A2 P05177 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
CHRM2 P08172 2/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
MAPT P10636 2/20 0.41
LMNA P02545 1/20 0.41
CHRM1 P11229 1/20 0.41
ALOX15 P16050 1/20 0.41
TSHR P16473 1/20 0.41
ACHE P22303 1/20 0.41
KCNH2 Q12809 1/20 0.41
HIF1A Q16665 1/20 0.41
KDM4E B2RXH2 1/20 0.41
USP2 O75604 1/20 0.41
ALDH1A1 P00352 1/20 0.41
TP53 P04637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7921351 0.89 CYP1A2 (0.57) MCHR1CYP1A2CYP2C9CYP2C19CHRM2
SCHEMBL7933096 0.85 MEN1 (0.51) MCHR1CYP1A2CYP2C9CYP2C19CHRM2
SCHEMBL7927083 0.85 MEN1 (0.51) MCHR1CYP1A2CYP2C9CYP2C19CHRM2
SCHEMBL7930783 0.81 ALDH1A1 (0.52) CYP2A6CYP1A2CYP2C19MEN1KMT2A
1,2-Dipropoxybenzene SCHEMBL578657 0.80 CYP1A2 (0.56) MCHR1CYP2A6CYP1A2CYP2C9CYP2C19
1,2-Dipropoxybenzene SCHEMBL29428926 0.80 CYP1A2 (0.56) MCHR1CYP2A6CYP1A2CYP2C9CYP2C19
SCHEMBL1805791 0.80 CYP1A2 (0.47) MCHR1CYP2A6CYP1A2CYP2C9CYP2C19
SCHEMBL11333941 0.79 MAPT (0.52) MCHR1CYP2A6CYP1A2CYP2C9CYP2C19
SCHEMBL8863052 0.79 CYP2A6 (0.56) MCHR1CYP2A6MEN1KMT2AHTR1B
SCHEMBL7928280 0.79 MCHR1 (0.58) MCHR1CYP2A6CYP1A2CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0661350-B1 Quinizarin compound, method for production thereof, and use therefor NIPPON CATALYTIC CHEM IND (JP) 2001-08-22 EP disclosed
US-5817843-A Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1998-10-06 US disclosed
US-5608091-A SHEETS FOR HEAT EXCHANGING AND OPTICAL RECORDING MATERIAL NIPPON SHOKUBAI CO., LTD. (JP) 1997-03-04 US disclosed
EP-0661350-A1 Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1995-07-05 EP disclosed