SCHEMBL7928280

SCHEMBL7928280

CCCOc1cccc(OCCC)c1N

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCHR1 Q99705 4/20 0.58
CYP1A2 P05177 1/20 0.55
CYP2C9 P11712 1/20 0.55
CYP2C19 P33261 1/20 0.55
ALDH1A1 P00352 3/20 0.52
GAA P10253 2/20 0.52
KDM4E B2RXH2 2/20 0.52
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
MAPT P10636 2/20 0.52
HTT P42858 2/20 0.52
USP2 O75604 1/20 0.52
TP53 P04637 1/20 0.52
POLB P06746 1/20 0.52
CASP1 P29466 1/20 0.52
CASP7 P55210 1/20 0.52
ATM Q13315 1/20 0.52
TLR8 Q9NR97 1/20 0.49
CYP2A6 P11509 1/20 0.47
HTR2C P28335 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11261747 0.92 CYP1A2 (0.58) MCHR1CYP1A2CYP2C9CYP2C19ALDH1A1
SCHEMBL30967549 0.92 CYP1A2 (0.58) MCHR1CYP1A2CYP2C9CYP2C19ALDH1A1
SCHEMBL11703860 0.90 MCHR1 (0.50) MCHR1CYP1A2CYP2C9CYP2C19ALDH1A1
SCHEMBL7921354 0.88 CYP1A2 (0.70) MCHR1CYP1A2CYP2C9CYP2C19MEN1
SCHEMBL11868776 0.88 MCHR1 (0.49) MCHR1CYP1A2CYP2C9CYP2C19ALDH1A1
SCHEMBL3784534 0.88 MCHR1 (0.49) MCHR1CYP1A2CYP2C9CYP2C19ALDH1A1
SCHEMBL19699786 0.88 MCHR1 (0.49) MCHR1CYP1A2CYP2C9CYP2C19ALDH1A1
SCHEMBL3786687 0.85 MCHR1 (0.46) MCHR1CYP1A2CYP2C9CYP2C19ALDH1A1
SCHEMBL7927085 0.85 MCHR1 (0.61) MCHR1CYP1A2CYP2C9CYP2C19ALDH1A1
SCHEMBL7933101 0.85 MCHR1 (0.61) MCHR1CYP1A2CYP2C9CYP2C19ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0661350-B1 Quinizarin compound, method for production thereof, and use therefor NIPPON CATALYTIC CHEM IND (JP) 2001-08-22 EP disclosed
US-5817843-A Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1998-10-06 US disclosed
US-5608091-A SHEETS FOR HEAT EXCHANGING AND OPTICAL RECORDING MATERIAL NIPPON SHOKUBAI CO., LTD. (JP) 1997-03-04 US disclosed
EP-0661350-A1 Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1995-07-05 EP disclosed