Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18122098 | 0.91 | CYP1A2 (0.58) | MCHR1L3MBTL1CYP1A2CYP2C19CYP2C9 | |
| SCHEMBL7928280 | 0.88 | MCHR1 (0.58) | MCHR1CYP1A2CYP2C19CYP2C9KDM4E | |
| SCHEMBL17887304 | 0.85 | L3MBTL1 (0.55) | L3MBTL1CYP1A2CYP2C19KDM4EGAA | |
| SCHEMBL2061557 | 0.84 | L3MBTL1 (0.46) | L3MBTL1CYP1A2CYP2C19CYP2C9KDM4E | |
| SCHEMBL30967549 | 0.81 | CYP1A2 (0.58) | MCHR1CYP1A2CYP2C19CYP2C9KDM4E | |
| SCHEMBL11261747 | 0.81 | CYP1A2 (0.58) | MCHR1CYP1A2CYP2C19CYP2C9KDM4E | |
| SCHEMBL8216509 | 0.81 | L3MBTL1 (0.50) | MCHR1L3MBTL1CYP1A2CYP2C19CYP2C9 | |
| SCHEMBL9868970 | 0.81 | HTR1B (0.53) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL29635826 | 0.80 | L3MBTL1 (0.69) | L3MBTL1CYP1A2CYP2C19CYP2C9KDM4E | |
| SCHEMBL255561 | 0.80 | L3MBTL1 (0.69) | L3MBTL1CYP1A2CYP2C19CYP2C9KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170355717-A1 | NOVEL 5,6-DIHYDRO-4H-BENZO[B]THIENO-[2,3-D]AZEPINE DERIVATIVES | PULMOCIDE LIMITED (GB) | 2017-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170355717-A1 | NOVEL 5,6-DIHYDRO-4H-BENZO[B]THIENO-[2,3-D]AZEPINE DERIVATIVES | ZC3HAV1, DHX15, AZI2 | MCHR1 3133/4885L3MBTL1 3002/4885CYP1A2 1359/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.