Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3780735 | 0.91 | CYP1A2 (0.58) | MCHR1NPC1RAB9ACYP1A2CYP2C9 | |
| SCHEMBL7928280 | 0.88 | MCHR1 (0.58) | MCHR1CSNK2A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL3791890 | 0.85 | ALDH1A1 (0.53) | RAB9AL3MBTL1MAPTGAAKDM4E | |
| SCHEMBL30967549 | 0.81 | CYP1A2 (0.58) | MCHR1CSNK2A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL15473216 | 0.81 | ALDH1A1 (0.54) | MCHR1NPC1RAB9ACSNK2A1CYP1A2 | |
| SCHEMBL11261747 | 0.81 | CYP1A2 (0.58) | MCHR1CSNK2A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL3790085 | 0.80 | L3MBTL1 (0.59) | NPC1RAB9ACSNK2A1CYP1A2CYP2C9 | |
| SCHEMBL3786544 | 0.79 | L3MBTL1 (0.58) | MCHR1NPC1RAB9ACSNK2A1L3MBTL1 | |
| SCHEMBL8083661 | 0.79 | RAB9A (0.49) | MCHR1NPC1RAB9ACSNK2A1CYP1A2 | |
| SCHEMBL11703860 | 0.79 | MCHR1 (0.50) | MCHR1CYP1A2CYP2C9CYP2C19MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2754651-B1 | NITROBENZENE COMPOUND MANUFACTURING METHOD | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2017-12-06 | — | — | EP | disclosed |
| US-9006477-B2 | Method for producing nitrobenzene compound | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2015-04-14 | — | — | US | disclosed |
| US-20140163256-A1 | METHOD FOR PRODUCING NITROBENZENE COMPOUND | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2014-06-12 | — | — | US | disclosed |
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-04-08 | — | — | US | disclosed |
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | NISCH, BLVRB, BBOX1 | MCHR1 4010/4885NPC1 724/4885RAB9A 1357/4885 |
| US-20140163256-A1 | METHOD FOR PRODUCING NITROBENZENE COMPOUND | NOX1, NOS2, CYB5R3 | MCHR1 1145/4885NPC1 4336/4885RAB9A 1223/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.