Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL866370 | 0.70 | HTT (0.39) | HTTTSHRCYP3A4MAPK1ALDH1A1 | |
| Methane SCHEMBL28424227 | 0.69 | HTT (0.38) | HTTTSHRALDH1A1GAANPC1 | |
| SCHEMBL6905998 | 0.65 | MAPT (0.45) | HTTTSHRCYP3A4MAPK1ALDH1A1 | |
| SCHEMBL7188472 | 0.65 | HTT (0.36) | HTTTSHRALDH1A1GAA | |
| SCHEMBL30441453 | 0.65 | HTT (0.36) | HTTTSHRALDH1A1GAA | |
| SCHEMBL29232865 | 0.65 | HTT (0.40) | HTTTSHRALDH1A1GAA | |
| SCHEMBL28209601 | 0.64 | HTT (0.32) | HTT | |
| SCHEMBL13291858 | 0.62 | HTT (0.34) | HTTTSHRALDH1A1GAA | |
| SCHEMBL3483012 | 0.61 | MAPT (0.36) | HTTTSHRCYP3A4MAPK1ALDH1A1 | |
| SCHEMBL3208997 | 0.61 | POLB (0.42) | TSHRALDH1A1GAANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1157047-A1 | LIGANDS AND CATALYSTS FOR PRODUCING ELASTOMERIC PROPYLENE POLYMERS | BP Corporation North America Inc. (US) | 2001-11-28 | — | — | EP | disclosed |
| WO-2000035975-A1 | LIGANDS AND CATALYSTS FOR PRODUCING ELASTOMERIC PROPYLENE POLYMERS | BP CORPORATION NORTH AMERICA INC. (US) | 2000-06-22 | — | — | WO | disclosed |