SCHEMBL7188472

SCHEMBL7188472

Cc1cc2c(cc1C)CC(C)(CO)C2

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.36
ALDH1A1 P00352 1/20 0.36
GAA P10253 1/20 0.36
TSHR P16473 1/20 0.36
EPHX1 P07099 1/20 0.36
KMT2A Q03164 2/20 0.33
MEN1 O00255 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30441453 1.00 HTT (0.36) HTTALDH1A1GAATSHREPHX1
SCHEMBL28207585 0.79 ADRA2A (0.36) HTTALDH1A1GAAEPHX1
SCHEMBL28207065 0.79 ADRA2A (0.36) HTTALDH1A1GAAEPHX1
SCHEMBL29364253 0.79 ADRA2A (0.36) HTTALDH1A1GAAEPHX1
SCHEMBL30441294 0.77 UGT2B17 (0.32)
SCHEMBL30492715 0.77 UGT2B17 (0.32)
SCHEMBL7185718 0.74 BUB1 (0.40) ALDH1A1EPHX1KMT2A
SCHEMBL30492670 0.74 BUB1 (0.40) ALDH1A1EPHX1KMT2A
SCHEMBL24440127 0.74
SCHEMBL13291858 0.74 HTT (0.34) HTTALDH1A1GAATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240238177-A1 USE OF VOLATILE COMPOUNDS TO MODULATE THE PERCEPTION OF FLORAL MUGUET FIRMENICH SA (CH) 2024-07-18 US claimed
CN-116807912-A Use of volatile components to limit or eliminate perception of malodor 弗门尼舍有限公司 2023-09-29 CN claimed
US-20230233425-A1 USE OF VOLATILE COMPOSITIONS TO LIMIT OR ELIMINATE THE PERCEPTION OF MALODOR FIRMENICH SA (CH) 2023-07-27 US claimed
US-20220008302-A1 USE OF VOLATILE COMPOUNDS TO MODULATE THE PERCEPTION OF FLORAL MUGUET FIRMENICH & CIE (CH) 2022-01-13 US claimed
EP-3853328-A2 USE OF VOLATILE COMPOUNDS TO MODULATE THE PERCEPTION OF FLORAL MUGUET Firmenich SA (CH) 2021-07-28 EP claimed
US-20200345601-A1 USE OF VOLATILE COMPOSITIONS TO LIMIT OR ELIMINATE THE PERCEPTION OF MALODOR FIRMENICH SA (CH) 2020-11-05 US claimed
EP-3713610-A2 USE OF VOLATILE COMPOSITIONS TO LIMIT OR ELIMINATE THE PERCEPTION OF MALODOR Firmenich SA (CH) 2020-09-30 EP claimed
CN-111432851-A Use of volatile ingredients to limit or eliminate perception of malodour 弗门尼舍有限公司 2020-07-17 CN claimed
WO-2020127325-A2 USE OF VOLATILE COMPOUNDS TO MODULATE THE PERCEPTION OF FLORAL MUGUET FIRMENICH SA (CH) 2020-06-25 WO claimed
WO-2019101821-A2 USE OF VOLATILE COMPOSITIONS TO LIMIT OR ELIMINATE THE PERCEPTION OF MALODOR FIRMENICH SA (CH) 2019-05-31 WO claimed
EP-1022265-B1 2-Indanemethanol derivatives and their use as perfuming ingredients FIRMENICH & CIE (CH) 2003-03-26 EP claimed
US-6323173-B1 COMPOUNDS WHICH DEVELOP FRESH, HUMIC, VERY PLEASANT FRAGRANCE OF LILY OF THE VALLEY TYPE; GOOD STABILITY AND EXCELLENT TENACITY FIRMENICH SA (CH) 2001-11-27 US claimed
EP-1022265-A1 2-Indanemethanol derivatives and their use as perfuming ingredients FIRMENICH SA (CH) 2000-07-26 EP claimed
US-20250009924-A1 Indane Derivatives for Malodor Counteraction FIRMENICH SA (CH) 2025-01-09 US disclosed
US-20240238177-A1 USE OF VOLATILE COMPOUNDS TO MODULATE THE PERCEPTION OF FLORAL MUGUET FIRMENICH SA (CH) 2024-07-18 US disclosed
CN-113873884-B Arthropod control composition 弗门尼舍有限公司 2024-06-14 CN disclosed
EP-1022265-B1 2-Indanemethanol derivatives and their use as perfuming ingredients FIRMENICH & CIE (CH) 2003-03-26 EP disclosed
US-6323173-B1 COMPOUNDS WHICH DEVELOP FRESH, HUMIC, VERY PLEASANT FRAGRANCE OF LILY OF THE VALLEY TYPE; GOOD STABILITY AND EXCELLENT TENACITY FIRMENICH SA (CH) 2001-11-27 US disclosed
JP-2000212111-A 2-INDANEMETHANOL DERIVATIVE, ITS USE, PERFUME COMPOSITION, PERFUMING PRODUCT, PRODUCTION OF THE SAME DERIVATIVE AND STARTING COMPOUND FOR THAT PURPOSE FIRMENICH SA 2000-08-02 JP disclosed
EP-1022265-A1 2-Indanemethanol derivatives and their use as perfuming ingredients FIRMENICH SA (CH) 2000-07-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250009924-A1 Indane Derivatives for Malodor Counteraction MAL2, MTNR1A, LPO HTT 3615/4885ALDH1A1 150/4885GAA 1815/4885
US-20200345601-A1 USE OF VOLATILE COMPOSITIONS TO LIMIT OR ELIMINATE THE PERCEPTION OF MALODOR TAS2R8, TRPA1, TAS2R10 HTT 4370/4885ALDH1A1 831/4885GAA 993/4885
US-20230233425-A1 USE OF VOLATILE COMPOSITIONS TO LIMIT OR ELIMINATE THE PERCEPTION OF MALODOR TAS2R8, TRPA1, TAS2R10 HTT 4370/4885ALDH1A1 831/4885GAA 993/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.