SCHEMBL7928561

SCHEMBL7928561

O=C=Nc1ccccc1C(=O)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 3/20 0.52
GAA P10253 2/20 0.48
MAPT P10636 1/20 0.48
ALDH1A1 P00352 3/20 0.46
CYP3A4 P08684 1/20 0.42
ATM Q13315 3/20 0.42
CDC25B P30305 1/20 0.42
TDP1 Q9NUW8 2/20 0.41
HSP90AA1 P07900 1/20 0.41
PKM P14618 1/20 0.41
CCR6 P51684 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
TLR9 Q9NR96 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
SRD5A2 P31213 1/20 0.41
KMT2A Q03164 3/20 0.41
MEN1 O00255 2/20 0.41
USP2 O75604 2/20 0.41
NR4A1 P22736 1/20 0.41
CYP2C8 P10632 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30945800 0.88 CYP3A4 (0.48) AKR1C3GAAMAPTALDH1A1CYP3A4
SCHEMBL9957687 0.88 CYP3A4 (0.48) AKR1C3GAAMAPTALDH1A1CYP3A4
SCHEMBL30673912 0.86 AKR1C3 (0.56) AKR1C3MAPTCYP3A4ATMCDC25B
SCHEMBL30673917 0.86 AKR1C3 (0.56) AKR1C3GAAMAPTALDH1A1CYP3A4
SCHEMBL483540 0.86 AKR1C3 (0.46) AKR1C3GAAMAPTALDH1A1CYP3A4
SCHEMBL11397281 0.85 MAPT (0.50) AKR1C3GAAMAPTALDH1A1CYP3A4
SCHEMBL5145030 0.84 AKR1C3 (0.50) AKR1C3GAAMAPTALDH1A1CYP3A4
SCHEMBL3415350 0.84 CES2 (0.50) AKR1C3MAPTALDH1A1CYP3A4TDP1
SCHEMBL30673907 0.82 POLB (0.59) ALDH1A1CYP3A4TDP1NPSR1L3MBTL1
SCHEMBL4687669 0.82 ALDH1A1 (0.52) AKR1C3GAAMAPTALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117164531-B 2, 4-Disubstituted 4H-benzo [ d ] [1,3] oxazine series, preparation method and application thereof 江西师范大学 2025-06-24 CN claimed
CN-117164531-A 2, 4-disubstituted 4H-benzo [ d ] [1,3] oxazine series, preparation method and application thereof 江西师范大学 2023-12-05 CN claimed
CN-117164531-B 2, 4-Disubstituted 4H-benzo [ d ] [1,3] oxazine series, preparation method and application thereof 江西师范大学 2025-06-24 CN disclosed
WO-2024133996-A1 METHOD FOR PREPARING TRANSPARENT AND HEAT-SENSITIVE POLYCAPROLACTAM COATINGS ON POLYMER SUBSTRATES CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (ES) 2024-06-27 WO disclosed
CN-117164531-A 2, 4-disubstituted 4H-benzo [ d ] [1,3] oxazine series, preparation method and application thereof 江西师范大学 2023-12-05 CN disclosed
CN-105455764-A Flexible tube for an endoscope, adhesive for an endoscope, endoscope-type medical device, as well as method of producing a flexible tube for an endoscope and method of producing an endoscope-type medical device FUJIFILM CORP 2016-04-06 CN disclosed
WO-2012175680-A1 HIGH STYRENE HIGH VINYL STYRENE-BUTADIENE RUBBER WITH NARROW MOLECULAR WEIGHT DISTRIBUTION AND METHODS FOR PREPARATION THEREOF STYRON EUROPE GMBH (CH) 2012-12-27 WO disclosed
EP-1161481-A1 OPTICALLY ACTIVE LINEAR POLYMER USED AS LIGAND IN THE PREPARATION OF METALLIC COMPLEXES DESIGNED FOR ASYMMETRIC CATALYSIS RHODIA CHIMIE (FR) 2001-12-12 EP disclosed
WO-2000052081-A1 OPTICALLY ACTIVE LINEAR POLYMER USED AS LIGAND IN THE PREPARATION OF METALLIC COMPLEXES DESIGNED FOR ASYMMETRIC CATALYSIS RHODIA CHIMIE (FR) 2000-09-08 WO disclosed
US-4026697-A HERBICIDES AMERICAN CYANAMID COMPANY (US) 1977-05-31 US disclosed
US-3988300-A FOR CONTROLLING BROADLEAF WEEDS AND GRASSES AMERICAN CYANAMID COMPANY (US) 1976-10-26 US disclosed