SCHEMBL7928620

SCHEMBL7928620

C[Si](C)=[Ti](OC(=O)c1cccc2ccccc12)(OC(=O)c1cccc2ccccc12)(C1=CC=CC1)C1c2ccccc2-c2ccccc21

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.36
MEN1 O00255 5/20 0.36
ALDH1A1 P00352 4/20 0.36
CYP2C9 P11712 3/20 0.36
MAPT P10636 3/20 0.36
LMNA P02545 2/20 0.36
CYP1A2 P05177 2/20 0.36
CYP3A4 P08684 2/20 0.36
CYP2D6 P10635 2/20 0.36
HPGD P15428 2/20 0.36
CYP2C19 P33261 1/20 0.36
KCNH2 Q12809 1/20 0.36
POLB P06746 3/20 0.34
GAA P10253 1/20 0.34
CNR1 P21554 3/20 0.34
CNR2 P34972 3/20 0.34
ATM Q13315 1/20 0.34
HRH3 Q9Y5N1 1/20 0.33
CDC25B P30305 1/20 0.33
MTNR1A P48039 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7919260 0.86 KMT2A (0.37) KMT2AMEN1ALDH1A1CYP2C9MAPT
SCHEMBL8158140 0.84 APOBEC3A (0.33) KMT2AMEN1LMNAPOLBGAA
SCHEMBL7925654 0.83 KMT2A (0.32) KMT2AMEN1ALDH1A1CYP2C9MAPT
SCHEMBL7925779 0.82 POLB (0.39) KMT2AMEN1ALDH1A1CYP2C9MAPT
SCHEMBL7930962 0.80 MAPT (0.33) KMT2AMEN1MAPTLMNAPOLB
SCHEMBL7925495 0.80 LMNA (0.32) KMT2AALDH1A1LMNACYP1A2CYP2C19
SCHEMBL7928731 0.79 POLB (0.32) ALDH1A1POLB
SCHEMBL7919106 0.79 CYP1A2 (0.33) CYP2C9CYP1A2CYP3A4CYP2D6CYP2C19
SCHEMBL7925607 0.78 POLB (0.33) POLB
SCHEMBL7930300 0.78 POLB (0.31) POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0867454-B1 POLYMERIZATION CATALYST AND PROCESS FOR PRODUCING POLYMERS IDEMITSU KOSAN CO (JP) 2001-03-21 EP disclosed
US-6075102-A Polymerization catalyst and process for producing polymers IDEMITSU KOSAN CO., LTD. (JP) 2000-06-13 US disclosed
EP-0867454-A1 POLYMERIZATION CATALYST AND PROCESS FOR PRODUCING POLYMERS IDEMITSU KOSAN COMPANY LIMITED (JP) 1998-09-30 EP disclosed