SCHEMBL7930962

SCHEMBL7930962

C[Si](C)=[Ti](OC(=O)c1ccc(F)cc1)(OC(=O)c1ccc(F)cc1)(C1=CC=CC1)C1c2ccccc2-c2ccccc21

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.33
CASP3 P42574 1/20 0.33
SENP8 Q96LD8 1/20 0.33
SENP7 Q9BQF6 1/20 0.33
SENP6 Q9GZR1 1/20 0.33
NPC1 O15118 2/20 0.32
RAB9A P51151 2/20 0.32
KMT2A Q03164 2/20 0.32
POLB P06746 1/20 0.32
HTR2C P28335 2/20 0.31
GAA P10253 2/20 0.31
SLC6A4 P31645 1/20 0.31
SLC6A3 Q01959 1/20 0.31
MEN1 O00255 1/20 0.30
LMNA P02545 1/20 0.30
PKM P14618 1/20 0.30
ALOX15 P16050 1/20 0.30
FFAR2 O15552 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8158140 0.91 APOBEC3A (0.33) KMT2APOLBGAAMEN1LMNA
SCHEMBL7930752 0.85 MAPT (0.34) MAPTCASP3SENP8SENP7SENP6
SCHEMBL7925779 0.83 POLB (0.39) MAPTKMT2APOLBGAAMEN1
SCHEMBL7924699 0.82 NPC1 (0.30) NPC1RAB9AKMT2APOLB
SCHEMBL7928731 0.80 POLB (0.32) POLB
SCHEMBL7919106 0.80 CYP1A2 (0.33) POLB
SCHEMBL7928620 0.80 KMT2A (0.36) MAPTNPC1RAB9AKMT2APOLB
SCHEMBL7925607 0.79 POLB (0.33) POLB
SCHEMBL7930300 0.79 POLB (0.31) POLB
SCHEMBL7927839 0.79 POLB (0.31) POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0867454-B1 POLYMERIZATION CATALYST AND PROCESS FOR PRODUCING POLYMERS IDEMITSU KOSAN CO (JP) 2001-03-21 EP disclosed
EP-0867454-A1 POLYMERIZATION CATALYST AND PROCESS FOR PRODUCING POLYMERS IDEMITSU KOSAN COMPANY LIMITED (JP) 1998-09-30 EP disclosed