SCHEMBL7928645

SCHEMBL7928645

O=C(O)CCC(Cl)CCCCCl

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 4/20 0.41
TET2 Q6N021 3/20 0.38
KDM4A O75164 2/20 0.38
KDM4C Q9H3R0 2/20 0.38
KDM2A Q9Y2K7 2/20 0.38
TET3 O43151 1/20 0.38
CYP1A2 P05177 2/20 0.37
GABRP O00591 2/20 0.37
GABRD O14764 2/20 0.37
GABRA1 P14867 2/20 0.37
GABRB1 P18505 2/20 0.37
GABRG2 P18507 2/20 0.37
GABRB3 P28472 2/20 0.37
GABRA5 P31644 2/20 0.37
GABRA3 P34903 2/20 0.37
GABRA2 P47869 2/20 0.37
GABRB2 P47870 2/20 0.37
GABRA4 P48169 2/20 0.37
GABRE P78334 2/20 0.37
GABRA6 Q16445 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14698683 0.84 LMNA (0.48) FOLH1TET2KDM4AKDM4CKDM2A
SCHEMBL11765423 0.83 FOLH1 (0.55) FOLH1TET2KDM4AKDM4CKDM2A
SCHEMBL20496986 0.83 LMNA (0.48) FOLH1GSTK1LMNASLC22A6ENPEP
SCHEMBL5662022 0.83 LMNA (0.48) FOLH1GSTK1LMNASLC22A6ENPEP
SCHEMBL5472354 0.83 LMNA (0.48) FOLH1GSTK1LMNASLC22A6ENPEP
SCHEMBL27899472 0.81 LMNA (0.46) FOLH1GSTK1LMNASLC22A6ENPEP
SCHEMBL7615127 0.80 GPR84 (0.36) FOLH1LMNASLC22A6TSHR
SCHEMBL11805584 0.79 FFAR4 (0.58) SLC22A6TSHRHSD17B10MAPT
SCHEMBL31612692 0.78 FFAR4 (0.52) FOLH1TET2KDM4AKDM4CKDM2A
SCHEMBL15716787 0.78 AKR1B1 (0.50) SLC22A6TSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0828768-B1 HOMOPOLYMERS AND COPOLYMERS OF CATIONICALLY POLYMERIZABLE MONOMERS AND METHOD OF THEIR PREPARATION GOODRICH CO B F (US) 2001-04-18 EP claimed