SCHEMBL7928675

SCHEMBL7928675

O=C(OCl)C(=O)OC12CC3CC(CC(C3)C1)C2

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 4/20 0.39
NAAA Q02083 1/20 0.37
NPSR1 Q6W5P4 3/20 0.36
CYP17A1 P05093 3/20 0.36
EPHX2 P34913 2/20 0.36
THRB P10828 1/20 0.35
CYP2C9 P11712 1/20 0.35
EPHX1 P07099 2/20 0.34
CA2 P00918 1/20 0.34
TSHR P16473 1/20 0.33
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
HTT P42858 1/20 0.32
KMT2A Q03164 1/20 0.32
GLA P06280 1/20 0.32
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27736443 0.89 CYP19A1 (0.44) CYP19A1NAAANPSR1CYP17A1EPHX2
SCHEMBL7928678 0.83 CYP19A1 (0.41) CYP19A1NAAANPSR1CYP17A1EPHX2
SCHEMBL18395311 0.81 CYP19A1 (0.40) CYP19A1NAAANPSR1CYP17A1EPHX2
SCHEMBL8395205 0.81 NAAA (0.45) CYP19A1NAAANPSR1CYP17A1EPHX2
SCHEMBL21392499 0.79 CYP19A1 (0.39) CYP19A1NAAANPSR1CYP17A1EPHX2
SCHEMBL7183809 0.78 CYP19A1 (0.41) CYP19A1NAAANPSR1CYP17A1EPHX2
SCHEMBL2212076 0.78 CYP19A1 (0.43) CYP19A1NAAANPSR1CYP17A1EPHX2
SCHEMBL6411360 0.78 NAAA (0.40) CYP19A1NAAANPSR1CYP17A1EPHX2
SCHEMBL45476 0.78 NAAA (0.40) CYP19A1NAAANPSR1CYP17A1EPHX2
SCHEMBL16369107 0.77 CYP19A1 (0.40) CYP19A1NAAANPSR1CYP17A1EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0850929-B1 Novel bis(mono- and diperoxy-oxalates) derived from dihydroperoxides and alkyl and alkylperoxy halooxalates ATOFINA CHEM INC (US) 2001-06-27 EP disclosed
US-5837782-A POLYMERIZATION CATALYST ELF ATOCHEM NORTH AMERICA, INC. (US) 1998-11-17 US disclosed
EP-0850929-A1 Novel bis(mono- and diperoxy-oxalates) derived from dihydroperoxides and alkyl and alkylperoxy halooxalates ELF ATOCHEM NORTH AMERICA, INC. (US) 1998-07-01 EP disclosed