SCHEMBL7928918

SCHEMBL7928918

CCOC(=O)C1(F)CCCCC1=O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 4/20 0.39
CYP3A4 P08684 2/20 0.39
POLB P06746 1/20 0.38
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
CYP2D6 P10635 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
ATM Q13315 1/20 0.36
ALDH1A1 P00352 3/20 0.36
CYP2C9 P11712 1/20 0.36
TSHR P16473 1/20 0.36
OPRM1 P35372 4/20 0.34
MAPT P10636 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
KDM4E B2RXH2 1/20 0.34
HPGD P15428 1/20 0.34
HSD17B10 Q99714 1/20 0.34
F10 P00742 1/20 0.34
OPRD1 P41143 2/20 0.33
OPRK1 P41145 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2728151 0.98 ALDH1A1 (0.38) CYP2C19CYP3A4POLBMEN1KMT2A
SCHEMBL4152272 0.95 CYP2C19 (0.42) CYP2C19CYP3A4POLBMEN1KMT2A
SCHEMBL19841985 0.82 OPRM1 (0.46) CYP2C19CYP3A4OPRM1OPRD1OPRK1
SCHEMBL16925425 0.80 OPRM1 (0.47) CYP2C19CYP3A4POLBMEN1KMT2A
SCHEMBL30153499 0.79 NPSR1 (0.39) CYP2C19CYP3A4MEN1KMT2AALDH1A1
SCHEMBL9583269 0.79 NPSR1 (0.39) CYP2C19CYP3A4MEN1KMT2AALDH1A1
SCHEMBL1577155 0.79 ATM (0.45) CYP2C19CYP3A4POLBMEN1KMT2A
SCHEMBL19841974 0.79 OPRM1 (0.38) POLBMEN1KMT2AALDH1A1OPRM1
SCHEMBL19842011 0.79 OPRM1 (0.40) MEN1KMT2AOPRM1OPRD1OPRK1
SCHEMBL16925439 0.78 OPRM1 (0.40) CYP2C19CYP3A4POLBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-5213898-A None JP disclosed
US-11795138-B2 Process of fluorinating inorganic compounds by direct fluorination Fujian Yongjing Technology Co.,Ltd (CN) 2023-10-24 US disclosed
US-11795138-B2 Process of fluorinating inorganic compounds by direct fluorination Fujian Yongjing Technology Co.,Ltd (CN) 2023-10-24 US disclosed
US-20220135516-A1 Process of Fluorinating Inorganic Compounds by Direct Fluorination Fujian Yongjing Technology Co.,Ltd (CN) 2022-05-05 US disclosed
WO-2021031432-A1 PROCESS OF FLUORINATING INORGANIC OR ORGANIC COMPOUNDS BY DIRECT FLUORINATION FUJIAN YONGJING TECHNOLOGY CO., LTD (CN) 2021-02-25 WO disclosed
US-20210053911-A1 Process of Fluorinating Inorganic or Organic Compounds by Direct Fluorination FUJIAN YONGJING TECHNOLOGY CO., LTD (CN) 2021-02-25 US disclosed
EP-0781752-B1 Process for preparing fluorine-containing dicarbonyl compound DAIKIN IND LTD (JP) 2001-02-21 EP disclosed
EP-0667332-B1 PROCESS FOR PRODUCING FLUORINATED DICARBONYL COMPOUND DAIKIN IND LTD (JP) 1998-09-23 EP disclosed
EP-0781752-A1 Process for preparing fluorine-containing dicarbonyl compound DAIKIN INDUSTRIES, LIMITED (JP) 1997-07-02 EP disclosed
EP-0667332-A1 PROCESS FOR PRODUCING FLUORINATED DICARBONYL COMPOUND DAIKIN INDUSTRIES, LIMITED (JP) 1995-08-16 EP disclosed
US-5262385-A Pyrimidine ring containing MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1993-11-16 US disclosed
JP-H05213898-A NEW HALOGENATED CYCLOALKENECARBOXYLIC ACID DERIVATIVE AND HERBICIDE COMPRISING THE SAME AS ACTIVE INGREDIENT MITSUBISHI PETROCHEM CO LTD 1993-08-24 JP disclosed
EP-0468766-A1 Halogen-containing compounds, herbicidal composition containing the same as an active ingredient, and intermediary compounds therefor Mitsubishi Chemical Corporation (JP) 1992-01-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11795138-B2 Process of fluorinating inorganic compounds by direct fluorination AFF2, CYP4F2, AFF1 CYP2C19 59/4885CYP3A4 22/4885POLB 1841/4885
US-20210053911-A1 Process of Fluorinating Inorganic or Organic Compounds by Direct Fluorination CYP4F2, AFF2, CYP4F3 CYP2C19 57/4885CYP3A4 18/4885POLB 1889/4885
US-20220135516-A1 Process of Fluorinating Inorganic Compounds by Direct Fluorination AFF2, CYP4F2, AFF1 CYP2C19 59/4885CYP3A4 22/4885POLB 1841/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.