Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 18/20 | 0.57 |
| ▸ | PDE4B | Q07343 | 10/20 | 0.57 |
| ▸ | PDE4C | Q08493 | 10/20 | 0.57 |
| ▸ | PDE4D | Q08499 | 10/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7420754 | 0.87 | PDE4A (0.52) | PDE4APDE4BPDE4CPDE4DPOLB | |
| SCHEMBL3181116 | 0.82 | PDE4A (0.65) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7175088 | 0.81 | PDE4A (0.65) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL2995451 | 0.80 | PDE4A (0.62) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7913418 | 0.79 | PDE4A (0.59) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7420235 | 0.79 | PDE4A (0.61) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4637671 | 0.79 | PDE4A (0.61) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6885590 | 0.79 | PDE4A (0.71) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7341124 | 0.79 | PDE4A (0.78) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7363361 | 0.79 | PDE4B (0.51) | PDE4APDE4BPDE4CPDE4DPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248769-B1 | ANTIINFLAMMATORY AGENT | EURO-CELTIQUE S.A. (LU) | 2001-06-19 | — | — | US | disclosed |