Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 12/20 | 0.52 |
| ▸ | PDE4B | Q07343 | 11/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 10/20 | 0.52 |
| ▸ | PDE4C | Q08493 | 9/20 | 0.52 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7928933 | 0.87 | PDE4A (0.57) | PDE4APDE4BPDE4DPDE4CPOLB | |
| SCHEMBL6889943 | 0.87 | PDE4A (0.60) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL7175088 | 0.81 | PDE4A (0.65) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL7320061 | 0.78 | PDE4A (0.48) | PDE4APDE4BPDE4DPDE4CPOLB | |
| SCHEMBL8770917 | 0.77 | ACHE (0.48) | PDE4APDE4BPDE4DPDE4CSTAT3 | |
| SCHEMBL9283831 | 0.77 | PDE4B (0.53) | PDE4APDE4BPDE4DPDE4CPOLB | |
| SCHEMBL7357352 | 0.76 | PDE4B (0.53) | PDE4APDE4BPDE4DPDE4CPOLB | |
| SCHEMBL7913418 | 0.76 | PDE4A (0.59) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL6229209 | 0.76 | PDE4B (0.50) | PDE4APDE4BPDE4DPDE4CPOLB | |
| SCHEMBL2988958 | 0.76 | PDE4A (0.63) | PDE4APDE4BPDE4DPDE4CPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248769-B1 | ANTIINFLAMMATORY AGENT | EURO-CELTIQUE S.A. (LU) | 2001-06-19 | — | — | US | disclosed |
| US-6103749-A | PHENYL IMIDAZOLE COMPOUNDS USEFUL FOR TREATMENT OF ASTHMA, ALLERGIES, INFLAMMATION AND DEPRESSION | EURO-CELTIQUE S.A. (LU) | 2000-08-15 | — | — | US | disclosed |
| US-5922751-A | BRONCHODILATOR AND ANTIINFLAMMATORY AGENT WITHOUT UNDESIRABLE CARDIOVASCULAR STIMULATION CAUSED BY PHOSPHODIESTERASE III INHIBITOR | EURO-CELTIQUE, S.A. (LU) | 1999-07-13 | — | — | US | disclosed |
| EP-0766676-A4 | COMPOUNDS FOR AND METHOD OF INHIBITING PHOSPHODIESTERASE IV | EURO CELTIQUE SA (LU) | 1998-07-08 | — | — | EP | disclosed |
| EP-0766676-A1 | COMPOUNDS FOR AND METHOD OF INHIBITING PHOSPHODIESTERASE IV | Euroceltique S.A. (LU) | 1997-04-09 | — | — | EP | disclosed |
| WO-1996000218-A1 | COMPOUNDS FOR AND METHOD OF INHIBITING PHOSPHODIESTERASE IV | EURO-CELTIQUE, S.A. (LU) | 1996-01-04 | — | — | WO | disclosed |