Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 2/20 | 0.31 |
| ▸ | CXCR5 | P32302 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 3/20 | 0.31 |
| ▸ | RAB9A | P51151 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7921532 | 0.85 | GHSR (0.41) | GHSREPHX2DPP8DPP9MAPT | |
| SCHEMBL7916929 | 0.85 | GHSR (0.41) | GHSREPHX2DPP8DPP9MAPT | |
| SCHEMBL7920225 | 0.74 | GHSR (0.37) | GHSREPHX2DPP8DPP9DDB1 | |
| SCHEMBL1425219 | 0.73 | GHSR (0.53) | GHSREPHX2CXCR5 | |
| SCHEMBL29707280 | 0.73 | GHSR (0.53) | GHSREPHX2CXCR5 | |
| SCHEMBL31240165 | 0.72 | GHSR (0.41) | GHSRNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL5416762 | 0.72 | GHSR (0.52) | GHSREPHX2DPP8DPP9CA12 | |
| SCHEMBL5034413 | 0.72 | GHSR (0.52) | GHSREPHX2DPP8DPP9CA12 | |
| SCHEMBL5390112 | 0.71 | CXCR5 (0.46) | GHSRCXCR5 | |
| SCHEMBL5404964 | 0.70 | GHSR (0.47) | GHSREPHX2DPP8DPP9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010042473-A1 | BIARYL SPIROAMINOOXAZOLINE ANALOGUES AS ALPHA2C ADRENERGIC RECEPTOR MODULATORS | SCHERING CORPORATION (US) | 2010-04-15 | — | — | WO | disclosed |