Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 2/20 | 0.47 |
| ▸ | CNR2 | P34972 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | GHSR | Q92847 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7932093 | 0.86 | ROCK1 (0.43) | ROCK1CNR2MEN1KMT2APOLB | |
| SCHEMBL7934185 | 0.86 | MAPT (0.54) | MEN1KMT2APOLBMAPTSMN1; SMN2 | |
| SCHEMBL7930900 | 0.85 | MAPT (0.49) | ROCK1CNR2MEN1KMT2APOLB | |
| SCHEMBL7928073 | 0.81 | TRPV1 (0.42) | — | |
| SCHEMBL7931544 | 0.75 | CNR2 (0.50) | CNR2MEN1KMT2APOLBMAPT | |
| SCHEMBL7930354 | 0.73 | SMN1; SMN2 (0.47) | CNR2MEN1KMT2APOLBMAPT | |
| SCHEMBL1937367 | 0.73 | KDR (0.56) | CNR2MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL23928620 | 0.72 | MEN1 (0.81) | MEN1KMT2APOLBMAPTSMN1; SMN2 | |
| SCHEMBL3367808 | 0.70 | EGLN1 (0.72) | CNR2MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL13500816 | 0.70 | SLC2A1 (0.71) | CNR2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010059836-A1 | SUBSTITUTED AZA-BRIDGED BICYCLICS FOR CARDIOVASCULAR AND CNS DISEASE | DECODE GENETICS EHF (IS) | 2010-05-27 | — | — | WO | disclosed |