Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | RARA | P10276 | 1/20 | 0.30 |
| ▸ | RARB | P10826 | 1/20 | 0.30 |
| ▸ | RARG | P13631 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7922994 | 0.83 | RXRA (0.35) | RXRARXRBRARARARBRARG | |
| SCHEMBL7931972 | 0.76 | RXRA (0.38) | RXRARXRBRARARARBRARG | |
| SCHEMBL7931979 | 0.73 | RARB (0.36) | RXRARXRBRARARARBRARG | |
| SCHEMBL7929418 | 0.72 | RARB (0.50) | RXRARXRBRARARARBRARG | |
| SCHEMBL7929520 | 0.71 | RXRA (0.42) | RXRARXRBRARARARBRARG | |
| SCHEMBL7929406 | 0.71 | RXRA (0.38) | RXRA | |
| SCHEMBL7922974 | 0.70 | RARB (0.43) | RXRARXRBRARARARBRARG | |
| SCHEMBL7949397 | 0.67 | CYP26A1 (0.34) | RXRARXRBRARARARBRARG | |
| SCHEMBL7922809 | 0.67 | RXRA (0.43) | RXRARXRBRARARARBRARG | |
| SCHEMBL10159988 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0879223-B1 | AROMATIC POLYCYCLIC RETINOID-TYPE DERIVATIVES, METHOD FOR PREPARING SAME, AND USE THEREOF FOR MAKING PHARMACEUTICAL AND COSMETIC COMPOSITIONS | CT EUROP DE BIOPROSPECTIVE CEB (FR) | 2001-11-07 | — | — | EP | claimed |
| US-6265423-B1 | SKIN DISORDERS; ANTICANCER AGENTS | CENTRE EUROPEEN DE BIOPROSPECTIVE-CEB (FR) | 2001-07-24 | — | — | US | claimed |