Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP26A1 | O43174 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 4/20 | 0.34 |
| ▸ | RXRB | P28702 | 3/20 | 0.34 |
| ▸ | RARA | P10276 | 7/20 | 0.32 |
| ▸ | RARB | P10826 | 7/20 | 0.32 |
| ▸ | RARG | P13631 | 7/20 | 0.32 |
| ▸ | RXRG | P48443 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7929520 | 0.84 | RXRA (0.42) | CYP26A1CYP3A4CYP26B1RXRARXRB | |
| SCHEMBL7931972 | 0.76 | RXRA (0.38) | CYP26A1CYP3A4CYP26B1RXRARXRB | |
| SCHEMBL7929418 | 0.74 | RARB (0.50) | CYP26A1CYP3A4CYP26B1RXRARXRB | |
| SCHEMBL7931979 | 0.73 | RARB (0.36) | CYP26A1CYP3A4CYP26B1RXRARXRB | |
| SCHEMBL9484572 | 0.68 | POLB (0.52) | CYP26A1CYP3A4CYP26B1RXRARXRB | |
| SCHEMBL9483500 | 0.68 | RXRA (0.42) | CYP26A1CYP3A4CYP26B1RXRARXRB | |
| SCHEMBL7929448 | 0.67 | NPC1 (0.43) | CYP26A1CYP3A4CYP26B1RXRARXRB | |
| SCHEMBL7929435 | 0.67 | RXRA (0.32) | RXRARXRBRARARARBRARG | |
| SCHEMBL9318355 | 0.67 | RXRA (0.41) | CYP26A1CYP3A4CYP26B1RXRARXRB | |
| SCHEMBL7922809 | 0.67 | RXRA (0.43) | CYP26A1CYP3A4CYP26B1RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265423-B1 | SKIN DISORDERS; ANTICANCER AGENTS | CENTRE EUROPEEN DE BIOPROSPECTIVE-CEB (FR) | 2001-07-24 | — | — | US | disclosed |