Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 14/20 | 0.44 |
| ▸ | RARB | P10826 | 13/20 | 0.44 |
| ▸ | RARA | P10276 | 13/20 | 0.44 |
| ▸ | RXRA | P19793 | 11/20 | 0.44 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7792396 | 0.85 | RARG (0.59) | RARGRARBRARARXRACYP26A1 | |
| SCHEMBL7792406 | 0.85 | RARG (0.59) | RARGRARBRARARXRACYP26A1 | |
| SCHEMBL7792400 | 0.85 | RARG (0.59) | RARGRARBRARARXRACYP26A1 | |
| SCHEMBL10864845 | 0.83 | RARB (0.43) | RARGRARBRARARXRACYP26A1 | |
| SCHEMBL10864842 | 0.83 | RARB (0.43) | RARGRARBRARARXRACYP26A1 | |
| SCHEMBL7947520 | 0.81 | RXRA (0.59) | RARGRARBRARARXRACYP26A1 | |
| SCHEMBL10865573 | 0.79 | RARA (0.39) | RARGRARBRARARXRACYP26A1 | |
| SCHEMBL7949412 | 0.78 | RXRA (0.71) | RARGRARBRARARXRACYP26A1 | |
| SCHEMBL7949393 | 0.78 | RXRA (0.53) | RARGRARBRARARXRACYP26A1 | |
| SCHEMBL7931932 | 0.78 | RARB (0.42) | RARGRARBRARARXRACYP26A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0879223-B1 | AROMATIC POLYCYCLIC RETINOID-TYPE DERIVATIVES, METHOD FOR PREPARING SAME, AND USE THEREOF FOR MAKING PHARMACEUTICAL AND COSMETIC COMPOSITIONS | CT EUROP DE BIOPROSPECTIVE CEB (FR) | 2001-11-07 | — | — | EP | disclosed |
| US-6265423-B1 | SKIN DISORDERS; ANTICANCER AGENTS | CENTRE EUROPEEN DE BIOPROSPECTIVE-CEB (FR) | 2001-07-24 | — | — | US | disclosed |