Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7929589 | 1.00 | HPGD (0.36) | HPGDSMN1; SMN2NPC1RAB9ACYP1A2 | |
| SCHEMBL7834315 | 0.81 | ESR1 (0.37) | HPGDSMN1; SMN2NPC1RAB9ACYP1A2 | |
| SCHEMBL7834312 | 0.81 | ESR1 (0.37) | HPGDSMN1; SMN2NPC1RAB9ACYP1A2 | |
| SCHEMBL4154025 | 0.76 | KMT2A (0.39) | HPGDCYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL3290298 | 0.76 | KMT2A (0.39) | HPGDCYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL7843664 | 0.73 | L3MBTL1 (0.45) | HPGDSMN1; SMN2NPC1RAB9ACYP1A2 | |
| SCHEMBL3289338 | 0.69 | NPSR1 (0.43) | HPGDSMN1; SMN2CYP1A2CYP2C19KMT2A | |
| SCHEMBL9222407 | 0.68 | HTT (0.47) | HPGDSMN1; SMN2NPC1RAB9ACYP1A2 | |
| SCHEMBL9222398 | 0.66 | HTT (0.47) | HPGDSMN1; SMN2NPC1RAB9ACYP1A2 | |
| SCHEMBL9222401 | 0.66 | HTT (0.47) | HPGDSMN1; SMN2NPC1RAB9ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248739-B1 | DNA POLYMERASE INHIBITORS EFFECTIVE AGAINST HERPESVIRUSES | PHARMACIA & UPJOHN COMPANY | 2001-06-19 | — | — | US | disclosed |