Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 3/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | ERCC5 | P28715 | 2/20 | 0.39 |
| ▸ | FEN1 | P39748 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9745314 | 0.78 | HTT (0.58) | L3MBTL1TDP1ALDH1A1HPGDNPC1 | |
| SCHEMBL7127425 | 0.75 | TDP1 (0.47) | TDP1ALDH1A1HPGDNPC1SMN1; SMN2 | |
| SCHEMBL7834315 | 0.73 | ESR1 (0.37) | L3MBTL1TDP1ALDH1A1HPGDNPC1 | |
| SCHEMBL7834312 | 0.73 | ESR1 (0.37) | L3MBTL1TDP1ALDH1A1HPGDNPC1 | |
| SCHEMBL7929591 | 0.73 | HPGD (0.36) | L3MBTL1TDP1ALDH1A1HPGDNPC1 | |
| SCHEMBL7929589 | 0.73 | HPGD (0.36) | L3MBTL1TDP1ALDH1A1HPGDNPC1 | |
| SCHEMBL4628086 | 0.73 | TSHR (0.65) | L3MBTL1TDP1ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL11666101 | 0.73 | ALDH1A1 (0.40) | L3MBTL1TDP1ALDH1A1HPGDNPC1 | |
| SCHEMBL8172213 | 0.72 | ALDH1A1 (0.53) | L3MBTL1TDP1ALDH1A1HPGDNPC1 | |
| SCHEMBL5775638 | 0.72 | ERCC5 (0.58) | TDP1ALDH1A1HPGDSMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140850-A1 | QUINOLINECARBOXAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2001-10-10 | — | — | EP | disclosed |
| US-6248739-B1 | DNA POLYMERASE INHIBITORS EFFECTIVE AGAINST HERPESVIRUSES | PHARMACIA & UPJOHN COMPANY | 2001-06-19 | — | — | US | disclosed |
| WO-2000040561-A1 | QUINOLINECARBOXAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2000-07-13 | — | — | WO | disclosed |