Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27676520 | 0.85 | ALDH1A1 (0.50) | ALDH1A1KDM4ELMNAHSD17B10MAPT | |
| SCHEMBL10983622 | 0.81 | MAPT (0.51) | ALDH1A1KDM4ELMNAHSD17B10MAPT | |
| SCHEMBL312873 | 0.81 | ALDH1A1 (0.47) | ALDH1A1KDM4ELMNAHSD17B10MAPT | |
| SCHEMBL28427985 | 0.81 | ALDH1A1 (0.47) | ALDH1A1KDM4ELMNAHSD17B10MAPT | |
| SCHEMBL312482 | 0.80 | ALDH1A1 (0.46) | ALDH1A1KDM4ELMNAHSD17B10MAPT | |
| SCHEMBL312618 | 0.80 | ALDH1A1 (0.46) | ALDH1A1KDM4ELMNAHSD17B10MAPT | |
| SCHEMBL4215150 | 0.80 | ALDH1A1 (0.46) | ALDH1A1KDM4ELMNAHSD17B10MAPT | |
| SCHEMBL7662392 | 0.76 | ALDH1A1 (0.46) | ALDH1A1KDM4ELMNAHSD17B10MAPT | |
| SCHEMBL17689783 | 0.76 | ALDH1A1 (0.43) | ALDH1A1KDM4ELMNAHSD17B10MAPT | |
| SCHEMBL587109 | 0.76 | LMNA (0.51) | ALDH1A1KDM4ELMNAHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010033444-A1 | CRYSTALLINE FORMS OF A 2-THIAZOLYL- 4-QUINOLINYL-OXY DERIVATIVE, A POTENT HCV INHIBITOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-03-25 | — | — | WO | disclosed |