Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.55 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 7/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | TNF | P01375 | 5/20 | 0.51 |
| ▸ | NOD1 | Q9Y239 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5371517 | 0.90 | ALDH1A1 (0.56) | PDE4BPDE4DMAPTTNFNOD1 | |
| SCHEMBL21260713 | 0.88 | PDE4B (0.52) | PDE4BPDE4DMEN1KMT2AMAPT | |
| SCHEMBL21260738 | 0.87 | MAPT (0.54) | PDE4BPDE4DMEN1KMT2AMAPT | |
| SCHEMBL21247126 | 0.87 | RAB9A (0.65) | PDE4BPDE4DMEN1KMT2AMAPT | |
| SCHEMBL21247383 | 0.85 | MAPT (0.73) | PDE4BPDE4DMEN1KMT2AMAPT | |
| SCHEMBL21247240 | 0.83 | TNF (0.60) | PDE4BPDE4DMEN1KMT2AMAPT | |
| SCHEMBL21247256 | 0.81 | RAB9A (0.60) | PDE4BPDE4DMEN1KMT2AMAPT | |
| SCHEMBL21247197 | 0.80 | MEN1 (0.61) | PDE4BPDE4DMEN1KMT2AMAPT | |
| SCHEMBL21260828 | 0.78 | HCAR2 (0.47) | PDE4BPDE4DMEN1KMT2AMAPT | |
| SCHEMBL21247163 | 0.78 | RAB9A (0.65) | MEN1KMT2AMAPTTNFNOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6306909-B1 | AMINOACID DERIVATIVES AND ESTERS | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2001-10-23 | — | — | US | disclosed |