Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 2/20 | 0.38 |
| ▸ | GABRD | O14764 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.38 |
| ▸ | GABRE | P78334 | 2/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.38 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.38 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.38 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 6/20 | 0.37 |
| ▸ | TET2 | Q6N021 | 3/20 | 0.34 |
| ▸ | KDM4A | O75164 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8075218 | 1.00 | GABRP (0.38) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7926313 | 1.00 | GABRP (0.38) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8139490 | 0.82 | GABRP (0.41) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8145321 | 0.82 | GABRP (0.41) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8466471 | 0.80 | PGD (0.34) | — | |
| SCHEMBL8466473 | 0.80 | PGD (0.34) | — | |
| SCHEMBL8132413 | 0.77 | CYP1A2 (0.34) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8132411 | 0.77 | CYP1A2 (0.34) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8144822 | 0.77 | GABRP (0.34) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8145424 | 0.77 | GABRP (0.34) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6177591-B1 | REACTING AN OPTICALLY ACTIVE 1-PHENYLETHYLAMINE WITH A RACEMIC DIHYDROCARBYLCARBOXYALKYLENE PHOSPHINE OXIDE; SEPARATING THE DIASTERIOMERIC SALTS USING THE DIFFERENCE IN SOLUBILITY IN A SOLVENT; DECOMPOSING THE SALT WITH AN ACID | NIPPON CHEMICAL INDUSTRIAL CO., LTD. (JP) | 2001-01-23 | — | — | US | disclosed |
| US-6121494-A | Method of producing optically active vinyl phosphine oxide | NIPPON CHEMICAL INDUSTRIAL CO., LTD. (JP) | 2000-09-19 | — | — | US | disclosed |