Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5271205 | 0.83 | KCNA5 (0.36) | NPSR1ALDH1A1NPC1RAB9APLA2G10 | |
| SCHEMBL6033646 | 0.83 | TRPM8 (0.38) | ALDH1A1KMT2ATRPM8ESR1ESR2 | |
| SCHEMBL7940014 | 0.81 | HDAC6 (0.41) | NPSR1ALDH1A1NPC1POLBHTT | |
| SCHEMBL75883 | 0.80 | NPSR1 (0.64) | NPSR1ALDH1A1NPC1POLBHTT | |
| SCHEMBL28148401 | 0.80 | NPSR1 (0.64) | NPSR1ALDH1A1NPC1POLBHTT | |
| SCHEMBL75885 | 0.80 | NPSR1 (0.64) | NPSR1ALDH1A1NPC1POLBHTT | |
| SCHEMBL5270823 | 0.79 | AKR1B1 (0.55) | NPSR1ALDH1A1NPC1POLBHTT | |
| SCHEMBL27478927 | 0.79 | NPSR1 (0.45) | NPSR1ALDH1A1NPC1POLBHTT | |
| Urea SCHEMBL23005263 | 0.78 | NPSR1 (0.61) | NPSR1ALDH1A1NPC1POLBHTT | |
| SCHEMBL28023499 | 0.78 | NPSR1 (0.61) | NPSR1ALDH1A1NPC1POLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6239108-B1 | Cell adhesion inhibitors | BIOGEN, INC. | 2001-05-29 | — | — | US | disclosed |