Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 4/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5271205 | 0.86 | KCNA5 (0.36) | ESR1ESR2SMN1; SMN2ALDH1A1 | |
| SCHEMBL27476794 | 0.84 | TRPM8 (0.38) | TRPM8LMNACYP3A4HSD17B1HSD17B2 | |
| SCHEMBL7929889 | 0.83 | NPSR1 (0.42) | TRPM8ESR1ESR2ALDH1A1KMT2A | |
| SCHEMBL3892110 | 0.83 | TRPM8 (0.47) | TRPM8LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL7416227 | 0.80 | SIGMAR1 (0.37) | TRPM8LMNACYP3A4HSD17B1HSD17B2 | |
| SCHEMBL6809913 | 0.79 | SIGMAR1 (0.36) | TRPM8LMNACYP3A4HSD17B1HSD17B2 | |
| SCHEMBL1954826 | 0.78 | SIGMAR1 (0.44) | TRPM8LMNACYP3A4HSD17B1HSD17B2 | |
| SCHEMBL5271237 | 0.77 | P2RX7 (0.36) | LMNASMN1; SMN2KMT2A | |
| SCHEMBL5994911 | 0.76 | SIGMAR1 (0.36) | TRPM8LMNACYP3A4HSD17B1HSD17B2 | |
| SCHEMBL5477921 | 0.74 | LMNA (0.45) | LMNAESR1MAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005122379-A9 | ALPHA-4 BETA-1 INTEGRIN LIGANDS FOR IMAGING AND THERAPY | UNIV CALIFORNIA (US) | 2006-03-09 | — | — | WO | disclosed |