SCHEMBL7929949

SCHEMBL7929949

CCCCc1cccc(CCCC)c1Nc1ccc2c(c1)C(=O)c1c(O)ccc(O)c1C2=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 7/20 0.47
CTSG P08311 5/20 0.47
MEN1 O00255 3/20 0.40
MAPT P10636 3/20 0.40
KMT2A Q03164 3/20 0.40
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
LMNA P02545 1/20 0.40
MAPK1 P28482 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
MAOA P21397 1/20 0.39
PTPRC P08575 2/20 0.38
ALDH1A1 P00352 1/20 0.38
CYP1A2 P05177 1/20 0.38
POLB P06746 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7921193 0.93 ELANE (0.45) ELANECTSGMEN1MAPTKMT2A
SCHEMBL7933258 0.89 MEN1 (0.44) MEN1MAPTKMT2ANPC1RAB9A
SCHEMBL7933233 0.78 DHODH (0.47) ELANECTSGMEN1MAPTKMT2A
SCHEMBL7933042 0.78 ELANE (0.48) ELANECTSGMEN1MAPTKMT2A
SCHEMBL7921179 0.76 MEN1 (0.44) MEN1MAPTKMT2ANPC1RAB9A
SCHEMBL7929799 0.76 MEN1 (0.46) MEN1MAPTKMT2ANPC1RAB9A
SCHEMBL7929902 0.76 ELANE (0.46) ELANECTSGMEN1MAPTKMT2A
SCHEMBL7921156 0.75 MEN1 (0.42) MEN1MAPTKMT2ANPC1RAB9A
SCHEMBL7927333 0.74 CLCN2 (0.46) MEN1MAPTKMT2ANPC1RAB9A
SCHEMBL7930594 0.73 SMN1; SMN2 (0.51) MEN1MAPTKMT2ANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0661350-B1 Quinizarin compound, method for production thereof, and use therefor NIPPON CATALYTIC CHEM IND (JP) 2001-08-22 EP disclosed
US-5817843-A Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1998-10-06 US disclosed
US-5608091-A SHEETS FOR HEAT EXCHANGING AND OPTICAL RECORDING MATERIAL NIPPON SHOKUBAI CO., LTD. (JP) 1997-03-04 US disclosed
EP-0661350-A1 Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1995-07-05 EP disclosed