SCHEMBL7933233

SCHEMBL7933233

Cc1cccc(C)c1Nc1ccc2c(c1)C(=O)c1c(O)ccc(O)c1C2=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 1/20 0.47
MEN1 O00255 5/20 0.46
KMT2A Q03164 5/20 0.46
MAPT P10636 5/20 0.46
MAOA P21397 3/20 0.46
CXCR2 P25025 1/20 0.43
SMN1; SMN2 Q16637 3/20 0.43
RAPGEF4 Q8WZA2 1/20 0.42
P2RY2 P41231 1/20 0.41
P2RY1 P47900 1/20 0.41
P2RY4 P51582 1/20 0.41
P2RY6 Q15077 1/20 0.41
P2RY12 Q9H244 1/20 0.41
TTR P02766 2/20 0.41
TDP1 Q9NUW8 3/20 0.40
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
MAPK1 P28482 2/20 0.40
NPSR1 Q6W5P4 2/20 0.40
LMNA P02545 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7928255 0.91 MAPT (0.41) DHODHMEN1KMT2AMAPTMAOA
SCHEMBL7928338 0.89 MAPT (0.47) MEN1KMT2AMAPTMAOACXCR2
SCHEMBL7929854 0.88 POLB (0.50) MEN1KMT2AMAPTCXCR2SMN1; SMN2
SCHEMBL7933258 0.83 MEN1 (0.44) MEN1KMT2AMAPTMAOASMN1; SMN2
SCHEMBL7921179 0.83 MEN1 (0.44) MEN1KMT2AMAPTMAOASMN1; SMN2
SCHEMBL7929799 0.83 MEN1 (0.46) DHODHMEN1KMT2AMAPTMAOA
SCHEMBL7921156 0.82 MEN1 (0.42) MEN1KMT2AMAPTMAOASMN1; SMN2
SCHEMBL7921193 0.80 ELANE (0.45) MEN1KMT2AMAPTMAOASMN1; SMN2
SCHEMBL7930873 0.79 MEN1 (0.56) DHODHMEN1KMT2AMAPTMAOA
SCHEMBL7929949 0.78 ELANE (0.47) MEN1KMT2AMAPTMAOASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0661350-B1 Quinizarin compound, method for production thereof, and use therefor NIPPON CATALYTIC CHEM IND (JP) 2001-08-22 EP disclosed
US-5817843-A Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1998-10-06 US disclosed
US-5608091-A SHEETS FOR HEAT EXCHANGING AND OPTICAL RECORDING MATERIAL NIPPON SHOKUBAI CO., LTD. (JP) 1997-03-04 US disclosed
EP-0661350-A1 Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1995-07-05 EP disclosed