Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.56 |
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | ALB | P02768 | 1/20 | 0.32 |
| ▸ | CFTR | P13569 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.31 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.31 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29314372 | 0.80 | CES2 (0.38) | TTRALBCFTRCHEK1DAPK3 | |
| SCHEMBL813690 | 0.80 | TTR (0.37) | TTRALBCFTRCHEK1DAPK3 | |
| SCHEMBL30206853 | 0.80 | TTR (0.37) | TTRALBCFTRCHEK1DAPK3 | |
| SCHEMBL896605 | 0.78 | CA1 (0.38) | TTRHIF1AHSD17B10GABRA1GABRB1 | |
| SCHEMBL15757953 | 0.78 | CHEK1 (0.37) | TTRGABRA1GABRB1GABRB2ALB | |
| SCHEMBL29611781 | 0.78 | CHEK1 (0.37) | TTRGABRA1GABRB1GABRB2ALB | |
| SCHEMBL350953 | 0.77 | TTR (0.64) | TTRERN1CYP1A2CYP2C9HIF1A | |
| SCHEMBL28104789 | 0.75 | CYP2C9 (0.37) | TTRCYP2C9CFTRMEN1LMNA | |
| Triiodophenol SCHEMBL338137 | 0.74 | TTR (1.00) | TTRERN1CYP1A2CYP2C9HIF1A | |
| SCHEMBL13191049 | 0.72 | TTR (0.56) | TTRERN1CYP1A2CYP2C9HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0707849-A1 | USE OF DERIVATIVES OF 2,4-BISUBSTITUTED PHENOLS AS 5-LIPOXIGENASE INHIBITORS | BOBEL246 S.L. (ES) | 1996-04-24 | — | — | EP | claimed |
| EP-0707849-B1 | USE OF DERIVATIVES OF 2,4-DISUBSTITUTED PHENOLS AS 5-LIPOXIGENASE INHIBITORS | BOBEL246 S L (ES) | 2001-12-19 | — | — | EP | disclosed |
| EP-0707849-A1 | USE OF DERIVATIVES OF 2,4-BISUBSTITUTED PHENOLS AS 5-LIPOXIGENASE INHIBITORS | BOBEL246 S.L. (ES) | 1996-04-24 | — | — | EP | disclosed |