Triiodophenol

Triiodophenol

SCHEMBL338137

Oc1c(I)cc(I)cc1I

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 2/20 1.00
ERN1 O75460 1/20 0.56
GABRA1 P14867 1/20 0.50
GABRB1 P18505 1/20 0.50
GABRB2 P47870 1/20 0.50
ALB P02768 1/20 0.50
MEN1 O00255 2/20 0.46
LMNA P02545 2/20 0.46
HTT P42858 2/20 0.46
KMT2A Q03164 2/20 0.46
HIF1A Q16665 2/20 0.44
HSD17B10 Q99714 2/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2C9 P11712 1/20 0.44
MAPK14 Q16539 2/20 0.41
CHEK1 O14757 1/20 0.41
DAPK3 O43293 1/20 0.41
RET P07949 1/20 0.41
PDGFRB P09619 1/20 0.41
PIM1 P11309 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7873607 0.88 TTR (0.78) TTRERN1GABRA1GABRB1GABRB2
SCHEMBL27280320 0.80 TTR (0.64) TTRERN1LMNAKMT2ARPS6KA3
SCHEMBL350953 0.80 TTR (0.64) TTRERN1MEN1LMNAHTT
SCHEMBL2049716 0.80 TTR (0.64) TTRERN1GABRA1GABRB1GABRB2
SCHEMBL7927726 0.80 GABRA1 (0.78) TTRERN1GABRA1GABRB1GABRB2
SCHEMBL11613562 0.80 TTR (0.65) TTRERN1GABRA1GABRB1GABRB2
SCHEMBL7932590 0.80 TTR (0.65) TTRERN1GABRA1GABRB1GABRB2
SCHEMBL1530279 0.80 TTR (0.65) TTRERN1GABRA1GABRB1GABRB2
SCHEMBL28010687 0.80 TTR (0.65) TTRERN1GABRA1GABRB1GABRB2
SCHEMBL11747447 0.80 TTR (0.65) TTRERN1GABRA1GABRB1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3595581-B1 VASCULAR PROSTHESIS FOR LEAK PREVENTION DURING ENDOVASCULAR ANEURYSM REPAIR TEXAS A & M UNIV SYS (US) 2026-02-25 EP claimed
EP-4376905-B1 COMPOSITIONS FOR EMBOLIZATION IBERHOSPITEX SA (ES) 2025-10-22 EP claimed
WO-2025120339-A1 AMINOALKYLATED BENZOXY COMPOUNDS FOR USE IN THE TREATMENT OF CARDIAC DISORDERS Szegedi Tudományegyetem (HU) 2025-06-12 WO claimed
US-12269790-B1 Process for the preparation of 2,4,6-triiodophenol derivatives BRACCO IMAGING S.P.A. (IT) 2025-04-08 US claimed
US-20250109094-A1 PROCESS FOR THE PREPARATION OF 2,4,6-TRIIODOPHENOL DERIVATIVES BRACCO IMAGING S.P.A. (IT) 2025-04-03 US claimed
CN-119095823-A Process for preparing 2,4, 6-triiodophenol derivatives 伯拉考成像股份公司 2024-12-06 CN claimed
CN-118549570-A Detection method of 13 disinfection byproducts in sediment 上海市环境科学研究院 2024-08-27 CN claimed
CN-114113370-B Analysis method of aromatic halogenated disinfection byproducts in water 东南大学 2024-03-26 CN claimed
WO-2023209165-A1 PROCESS FOR THE PREPARATION OF 2,4,6-TRIIODOPHENOL DERIVATIVES BRACCO IMAGING SPA (IT) 2023-11-02 WO claimed
CN-113466281-B Based on 1 Quantification method of total ginsenoside in H qNMR Shenmai injection 正大青春宝药业有限公司 2023-09-12 CN claimed
US-5411852-A A phenol with at least two iodo substituents EASTMAN KODAK COMPANY (US) 1995-05-02 US claimed
EP-0578765-A1 DELIVERY OF X-RAY CONTRAST AGENTS USING RECEPTOR MEDIATED ENDOCYTOSIS ADVANCED MAGNETICS INCORPORATED (US) 1994-01-19 EP claimed
WO-1992017216-A1 DELIVERY OF X-RAY CONTRAST AGENTS USING RECEPTOR MEDIATED ENDOCYTOSIS ADVANCED MAGNETICS, INC. (US) 1992-10-15 WO claimed
US-4727089-A RHEUMATIC DISEASES BISLAK, S.A. (ES) 1988-02-23 US claimed
US-4727090-A CARDIOVASCULAR DISORDERS BISLAK, S.A. (ES) 1988-02-23 US claimed
US-4677124-A TREATMENT OF ATHEROSCLEROSIS BISLAK, S.A. (ES) 1987-06-30 US claimed
EP-0147892-A2 Process for preparing and therapeutical applications of the 2,4,6-triiodophenol BISLAK, S.A. (ES) 1985-07-10 EP claimed
EP-0070198-B1 RADIATION-SENSITIVE COMPOSITION AND PATTERN-FORMATION METHOD USING THE SAME Hitachi, Ltd. (JP) 1985-06-19 EP claimed
EP-0070198-A1 Radiation-sensitive composition and pattern-formation method using the same Hitachi, Ltd. (JP) 1983-01-19 EP claimed
US-4179499-A HYDROXYPHENYL-SUBSTITUTED AMIDE, EDIBLE BINDER, BAIT, CARRIER LONZA LTD. (CH) 1979-12-18 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250109094-A1 PROCESS FOR THE PREPARATION OF 2,4,6-TRIIODOPHENOL DERIVATIVES TPO, IPO4, CYP4F2 TTR 63/4885ERN1 3476/4885GABRA1 4226/4885
US-12269790-B1 Process for the preparation of 2,4,6-triiodophenol derivatives TPO, IPO4, CYP4F2 TTR 63/4885ERN1 3476/4885GABRA1 4226/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.