Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.50 |
| ▸ | ERN1 | O75460 | 1/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL69776 | 0.80 | TTR (0.56) | TTRERN1ALBTDP1MEN1 | |
| SCHEMBL12817414 | 0.75 | TTR (0.50) | TTRERN1ALBTDP1MEN1 | |
| SCHEMBL29661971 | 0.73 | TP53 (0.53) | TTRALBALDH1A1TP53HPGD | |
| SCHEMBL8410940 | 0.72 | TTR (0.48) | TTRERN1ALBTDP1MEN1 | |
| SCHEMBL17378980 | 0.71 | MEN1 (0.50) | TTRTDP1MEN1LMNAHTT | |
| SCHEMBL2387045 | 0.70 | — | — | |
| SCHEMBL17378819 | 0.69 | THRA (0.37) | TTRTDP1MEN1LMNAKMT2A | |
| SCHEMBL27245311 | 0.69 | CA12 (0.45) | TTRALDH1A1LCKHPGDHSD17B10 | |
| SCHEMBL6720850 | 0.69 | TTR (0.50) | TTRERN1ALBTDP1MEN1 | |
| SCHEMBL7929986 | 0.69 | TTR (0.58) | TTRERN1ALBTDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0707849-B1 | USE OF DERIVATIVES OF 2,4-DISUBSTITUTED PHENOLS AS 5-LIPOXIGENASE INHIBITORS | BOBEL246 S L (ES) | 2001-12-19 | — | — | EP | disclosed |