SCHEMBL69776

SCHEMBL69776

Oc1c(I)cc(I)c(O)c1I

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 2/20 0.56
ALB P02768 1/20 0.43
MEN1 O00255 4/20 0.40
KMT2A Q03164 4/20 0.40
LMNA P02545 3/20 0.40
HTT P42858 3/20 0.40
TDP1 Q9NUW8 4/20 0.39
ERN1 O75460 1/20 0.39
USP2 O75604 3/20 0.38
TP53 P04637 3/20 0.38
MAPK14 Q16539 2/20 0.38
KDM4E B2RXH2 2/20 0.38
ALDH1A1 P00352 2/20 0.38
HSP90AA1 P07900 2/20 0.38
HPGD P15428 2/20 0.38
ALOX15 P16050 2/20 0.38
SLC6A2 P23975 2/20 0.38
MAPK1 P28482 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
HIF1A Q16665 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12817414 0.87 TTR (0.50) TTRALBMEN1KMT2ALMNA
SCHEMBL8410940 0.84 TTR (0.48) TTRALBMEN1KMT2ALMNA
SCHEMBL6720850 0.80 TTR (0.50) TTRALBMEN1KMT2ALMNA
SCHEMBL7929410 0.80 TTR (0.43) TTRALBMEN1KMT2ALMNA
SCHEMBL7929422 0.80 TTR (0.50) TTRALBMEN1KMT2ALMNA
SCHEMBL7932602 0.80 TTR (0.43) TTRALBMEN1KMT2ALMNA
SCHEMBL7930045 0.80 TTR (0.50) TTRALBMEN1KMT2ALMNA
SCHEMBL1686874 0.79 TTR (0.47) TTRALBMEN1KMT2ALMNA
SCHEMBL10891717 0.78 TTR (0.48) TTRALBMEN1KMT2ALMNA
SCHEMBL22897457 0.76 TDP1 (0.47) TTRALBMEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4011367-A1 COMPOUNDS FOR USE IN THE TREATMENT OF COVID-19 Dompe' Farmaceutici S.P.A. (IT) 2022-06-15 EP claimed
CN-108658733-B Preparation method of 2,4, 6-triiodoresorcinol 国药集团化学试剂有限公司 2021-05-25 CN claimed
CN-108658733-A A kind of preparation method of 2,4,6- triiodos resorcinol 国药集团化学试剂有限公司 2018-10-16 CN claimed
WO-2002003938-A1 IODO-CONTAINING ORGANIC COUPLERS FOR USE IN OXIDATIVE HAIR DYEING CLAIROL INCORPORATED (US) 2002-01-17 WO claimed
US-5372800-A X-ray contrast coating STERLING WINTHROP INC. (US) 1994-12-13 US claimed
EP-2841109-B1 PRODRUGS OF HYDROXYL-COMPRISING DRUGS ASCENDIS PHARMA AS (DK) 2026-04-15 EP disclosed
EP-3782649-B1 BIODEGRADABLE POLYETHYLENE GLYCOL BASED WATER-INSOLUBLE HYDROGELS ASCENDIS PHARMA AS (DK) 2025-05-14 EP disclosed
US-20240074995-A1 METHODS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH AN ABNORMAL INFLAMMATORY RESPONSES FIRST WAVE BIO, INC. 2024-03-07 US disclosed
US-11835860-B2 Resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-12-05 US disclosed
US-11835860-B2 Resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-12-05 US disclosed
US-20230381323-A1 RELEASABLE CONJUGATES FISH & RICHARDSON PC 2023-11-30 US disclosed
US-11814408-B2 Preparations of hydrophobic therapeutic agents, methods of manufacture and use thereof NICOX OPHTHALMICS, INC. (US) 2023-11-14 US disclosed
US-5372800-A X-ray contrast coating STERLING WINTHROP INC. (US) 1994-12-13 US disclosed
EP-0617969-A2 Compositions of iodophenyl esters and iodophenyl sulfonates for visualization of the gastrointestinal tract NYCOMED IMAGING AS (NO) 1994-10-05 EP disclosed
EP-0617970-A2 Compositions of iodophenyl esters and iodophenyl sulfonates in film-forming materials for visualization of the gastrointestinal tract NYCOMED IMAGING AS (NO) 1994-10-05 EP disclosed
US-5336484-A Contrast compound comprising an iodobenzene ester and a Group 2A metal salt of a carboxylated or sulfonated polysaccharide in a carrier; uniform coating; radiology STERLING WINTHROP INC. (US) 1994-08-09 US disclosed
US-5318769-A Compositions of iodophenyl esters for X-ray visualization of the gastrointestinal tract STERLING WINTHROP INC. (US) 1994-06-07 US disclosed
EP-0240459-A1 Curable compositions CIBA-GEIGY AG (CH) 1987-10-07 EP disclosed
US-3927125-A Method of preparing 2,4,6-triiodoresorcinol GRINEV ALEXEI NIKOLAEVICH 1975-12-16 US disclosed
US-3927125-A Method of preparing 2,4,6-triiodoresorcinol GRINEV ALEXEI NIKOLAEVICH 1975-12-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240074995-A1 METHODS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH AN ABNORMAL INFLAMMATORY RESPONSES FH, CS, ECHS1 TTR 872/4885ALB 2167/4885MEN1 3463/4885
US-20230381323-A1 RELEASABLE CONJUGATES GUSB, ABCB11, UGT2B7 TTR 1510/4885ALB 920/4885MEN1 2694/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.